Norepinephrine Stimulates Apoptosis in Adult Rat Ventricular Myocytes by Activation of the β-Adrenergic Pathway

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

1990 • 1,507 citations

Apoptosis in Myocytes in End-Stage Heart Failure

1996 • 1,446 citations

Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)

1997 • 1,082 citations

Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity.

1986 • 1,025 citations

Inhibition by cAMP of Ras-Dependent Activation of Raf

1993 • 955 citations

Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

1993 • 939 citations

Adrenergic effects on the biology of the adult mammalian cardiocyte.

1992 • 873 citations

Enhanced Myocardial Function in Transgenic Mice Overexpressing the β ₂ -Adrenergic Receptor

1994 • 745 citations

Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death.

1996 • 742 citations

Catecholamine cardiotoxicity

1985 • 692 citations

Stretch-induced programmed myocyte cell death.

1995 • 647 citations

Carvedilol Inhibits Clinical Progression in Patients With Mild Symptoms of Heart Failure

1996 • 643 citations

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes.

1994 • 560 citations

Acute Myocardial Infarction in Humans is Associated with Activation of Programmed Myocyte Cell Death in the Surviving Portion of the Heart

1996 • 515 citations

Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction. Evidence for independent regulation of growth and beating.

1985 • 485 citations

Medical Therapy Can Improve the Biological Properties of the Chronically Failing Heart

1996 • 468 citations

Role of free radicals in catecholamine-induced cardiomyopathy

1982 • 462 citations

Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response.

1990 • 444 citations

Apoptosis in pressure overload-induced heart hypertrophy in the rat.

1996 • 416 citations

Angiotensin II Induces Apoptosis of Adult Ventricular MyocytesIn Vitro

1997 • 413 citations

Cardiotrophin 1 (CT-1) Inhibition of Cardiac Myocyte Apoptosis via a Mitogen-activated Protein Kinase-dependent Pathway

1997 • 399 citations

Effect of Beta-Blockade on Mortality in Patients With Heart Failure: A Meta-Analysis of Randomized Clinical Trials

1997 • 365 citations

Death by Design

1997 • 364 citations

Programmed Myocyte Cell Death Affects the Viable Myocardium after Infarction in Rats

1996 • 340 citations

Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure.

1996 • 335 citations

Mechanisms of Apoptosis: Integration of Genetic, Biochemical, and Cellular Indicators

1994 • 320 citations

Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat

1997 • 304 citations

Atrial Natriuretic Peptide Induces Apoptosis in Neonatal Rat Cardiac Myocytes

1997 • 237 citations

Pressure- and Volume-Induced Left Ventricular Hypertrophies Are Associated With Distinct Myocyte Phenotypes and Differential Induction of Peptide Growth Factor mRNAs

1995 • 190 citations

Comparison of myocardial catecholamine balance in chronic congestive heart failure and in angina pectoris without failure

1984 • 182 citations

Programmed Cell Death and Expression of the Protooncogene bcl-2 in Myocytes during Postnatal Maturation of the Heart

1995 • 177 citations

Cardiomyopathy induced by cardiac Gs alpha overexpression

1997 • 163 citations

Deoxyribonuclease I in mammalian tissues. Specificity of inhibition by actin.

1981 • 150 citations

Myocyte death in heart failure

1996 • 123 citations

Chapter 4 Quantification of Apoptotic Events in Pure and Heterogeneous Populations of Cells Using the Flow Cytometer

1995 • 123 citations

Adult rat ventricular myocytes cultured in defined medium: phenotype and electromechanical function

1993 • 105 citations

Beta-adrenergic agonists stimulate the synthesis of noncontractile but not contractile proteins in cultured myocytes isolated from adult rat heart.

1990 • 68 citations

Calcium and catecholamines: Relevance to cardiomyopathies and significance in therapeutic strategies

1985 • 58 citations

Regulation of hypertrophy and atrophy in cultured adult heart cells.

1993 • 57 citations

Regulation of slow calcium channels of myocardial cells and vascular smooth muscle cells by cyclic nucleotides and phosphorylation

1994 • 56 citations

Contractile response of individual cardiac myocytes to norepinephrine declines with senescence

1992 • 46 citations

Abstract

1997 • 2 citations

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