Apoptosis in the Failing Human Heart

Some statistical methods useful in circulation research.

1980 • 3,978 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Apoptosis in Myocytes in End-Stage Heart Failure

1996 • 1,446 citations

Reperfusion injury induces apoptosis in rabbit cardiomyocytes.

1994 • 1,431 citations

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1993 • 1,144 citations

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.

1996 • 1,045 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

1994 • 664 citations

Stretch-induced programmed myocyte cell death.

1995 • 647 citations

Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme.

1995 • 643 citations

Structural basis of end-stage failure in ischemic cardiomyopathy in humans.

1994 • 583 citations

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes.

1994 • 560 citations

Gender differences and aging: Effects on the human heart

1995 • 552 citations

Acute Myocardial Infarction in Humans is Associated with Activation of Programmed Myocyte Cell Death in the Surviving Portion of the Heart

1996 • 515 citations

Proapoptotic Protein Bax Heterodimerizes with Bcl-2 and Homodimerizes with Bax via a Novel Domain (BH3) Distinct from BH1 and BH2

1996 • 462 citations

Cell death by apoptosis and its protective role against disease

1992 • 439 citations

Evidence of Apoptosis in Arrhythmogenic Right Ventricular Dysplasia

1996 • 421 citations

Structure-Function Analysis of Bcl-2 Protein

1995 • 419 citations

Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion.

1995 • 397 citations

The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo.

1995 • 385 citations

Programmed Myocyte Cell Death Affects the Viable Myocardium after Infarction in Rats

1996 • 340 citations

Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.

1989 • 338 citations

Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure.

1996 • 335 citations

Morphometry of human coronary capillaries during normal growth and the effect of age in left ventricular pressure-overload hypertrophy.

1992 • 315 citations

Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats

1996 • 275 citations

DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis.

1995 • 271 citations

The cellular basis of dilated cardiomyopathy in humans

1995 • 261 citations

Myocyte nuclear mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs.

1995 • 209 citations

Immunohistochemical analysis of Mcl-1 and Bcl-2 proteins in normal and neoplastic lymph nodes.

1994 • 163 citations

Myocardial blood flow distribution in patients with ischemic heart disease or dilated cardiomyopathy undergoing heart transplantation.

1993 • 146 citations

The Distal Pathway of Lipoprotein-induced Cholesterol Esterification, but Not Sphingomyelinase-induced Cholesterol Esterification, Is Energy-dependent

1996 • 137 citations

Apoptosis as a Possible Cause of Gradual Development of Complete Heart Block and Fatal Arrhythmias Associated With Absence of the AV Node, Sinus Node, and Internodal Pathways

1996 • 120 citations

Myocyte cellular hypertrophy is responsible for ventricular remodelling in the hypertrophied heart of middle aged individuals in the absence of cardiac failure

1994 • 114 citations

Ischaemic myocardial injury and ventricular remodelling

1993 • 112 citations

Myocardial blood flow in coronary artery disease: Studies at rest and during stress with inert gas washout techniques

1977 • 55 citations