Pressure- and Volume-Induced Left Ventricular Hypertrophies Are Associated With Distinct Myocyte Phenotypes and Differential Induction of Peptide Growth Factor mRNAs

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Wall stress and patterns of hypertrophy in the human left ventricle.

1975 • 2,343 citations

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

1993 • 1,420 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy.

1992 • 611 citations

Myosin isoenzyme changes in several models of rat cardiac hypertrophy.

1981 • 400 citations

Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes.

1990 • 377 citations

Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure.

1994 • 373 citations

Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding.

1993 • 359 citations

Function of the sarcoplasmic reticulum and expression of its Ca2(+)-ATPase gene in pressure overload-induced cardiac hypertrophy in the rat.

1990 • 339 citations

Quantitative structural analysis of the myocardium during physiologic growth and induced cardiac hypertrophy: A review

1986 • 315 citations

Regulation of myocardial Ca2+-ATPase and phospholamban mRNA expression in response to pressure overload and thyroid hormone.

1989 • 283 citations

Cytoskeletal Role in the Contractile Dysfunction of Hypertrophied Myocardium

1993 • 273 citations

Differential effects of transforming growth factor-beta 1 and phorbol myristate acetate on cardiac fibroblasts. Regulation of fibrillar collagen mRNAs and expression of early transcription factors.

1991 • 242 citations

Simple, rapid, and effective method of producing aortocaval shunts in the rat

1990 • 234 citations

Myocardial DNA synthesis in experimental cardiac hypertrophy

1968 • 214 citations

Hypertrophic stimuli induce transforming growth factor-beta 1 expression in rat ventricular myocytes.

1994 • 195 citations

Selective Activation of Cardiac Angiotensinogen Gene Expression in Post-infarction Ventricular Remodeling in the Rat

1993 • 194 citations

Culture of the terminally differentiated adult cardiac muscle cell: A light and scanning electron microscope study

1980 • 185 citations

Stereological measurement of cellular and subcellular hypertrophy and hyperplasia in the papillary muscle of adult rat

1980 • 183 citations

Nonsynchronous accumulation of alpha-skeletal actin and beta-myosin heavy chain mRNAs during early stages of pressure-overload--induced cardiac hypertrophy demonstrated by in situ hybridization.

1989 • 154 citations

Age-related differences in the expression of proto-oncogene and contractile protein genes in response to pressure overload in the rat myocardium.

1992 • 154 citations

Morphometry of exercise-induced right ventricular hypertrophy in the rat.

1983 • 152 citations

Induction of myocardial insulin-like growth factor-I gene expression in left ventricular hypertrophy.

1994 • 149 citations

Myocardial recruitment during ANF mRNA increase with volume overload in the rat

1986 • 147 citations

The vascular smooth muscle alpha-actin gene is reactivated during cardiac hypertrophy provoked by load.

1991 • 119 citations

Increased production of endothelin‐1 in the hypertrophied rat heart due to pressure overload

1993 • 118 citations

The renin-angiotensin system and volume overload-induced cardiac hypertrophy in rats. Effects of angiotensin converting enzyme inhibitor versus angiotensin II receptor blocker.

1993 • 117 citations

Differential regulation of skeletal alpha-actin transcription in cardiac muscle by two fibroblast growth factors.

1990 • 103 citations

Cellular versus myocardial basis for the contractile dysfunction of hypertrophied myocardium.

1991 • 89 citations

Structural analysis of pressure versus volume overload hypertrophy of cat right ventricle

1985 • 87 citations

Relevance of Blockade of Cardiac and Circulatory Angiotensin-Converting Enzyme for the Prevention of Volume Overload–Induced Cardiac Hypertrophy

1995 • 85 citations

Pressure-induced cardiac enlargement in neonatal and adult rats. Left ventricular functional characteristics and evidence of cardiac muscle cell proliferation in the neonate.

1978 • 85 citations

Postnatal Muscle Fiber Assembly: Localization of Newly Synthesized Myofibrillar Proteins

1970 • 75 citations

The renin-angiotensin system and volume overload-induced changes in cardiac collagen and elastin.

1994 • 73 citations

Structural remodeling of cardiac myocytes in rats with arteriovenous fistulas.

1988 • 71 citations

Analysis of thyroid hormone effects on myosin heavy chain gene expression in cardiac and soleus muscles using a novel dot-blot mRNA assay

1985 • 69 citations

Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats.

1994 • 67 citations

Phorbol esters and norepinephrine destabilize alpha 1B-adrenergic receptor mRNA in vascular smooth muscle cells.

1994 • 44 citations

Cardiocyte contractile performance in experimental biventricular volume-overload hypertrophy

1993 • 28 citations