The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure

Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure

1991 • 8,296 citations

Nonparametric Estimation from Incomplete Observations

1958 • 7,673 citations

Effects of Enalapril on Mortality in Severe Congestive Heart Failure

1987 • 4,763 citations

A Multiple Testing Procedure for Clinical Trials

1979 • 3,139 citations

Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure

1984 • 3,130 citations

Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure

1986 • 2,409 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design

1976 • 2,290 citations

Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure

1991 • 2,186 citations

Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy

1993 • 1,218 citations

A randomized trial of beta-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS). CIBIS Investigators and Committees.

1994 • 1,051 citations

Plasma norepinephrine in congestive heart failure

1978 • 919 citations

Adrenergic effects on the biology of the adult mammalian cardiocyte.

1992 • 873 citations

Effect of chronic beta-adrenergic receptor blockade in congestive cardiomyopathy.

1975 • 835 citations

Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger.

1992 • 489 citations

Effects of Vesnarinone on Morbidity and Mortality in Patients with Heart Failure

1993 • 482 citations

Long-term beta-blockade in dilated cardiomyopathy. Effects of short- and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol.

1989 • 447 citations

PROLONGATION OF SURVIVAL IN CONGESTIVE CARDIOMYOPATHY BY BETA-RECEPTOR BLOCKADE

1979 • 415 citations

Double-Blind, Placebo-Controlled Study of the Long-term Efficacy of Carvedilol in Patients With Severe Chronic Heart Failure

1995 • 385 citations

Carvedilol improves left ventricular function and symptoms in chronic heart failure: A double-blind randomized study

1995 • 375 citations

Effects of short- and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy

1994 • 331 citations

Effect of metoprolol on myocardial function and energetics in patients with nonischemic dilated cardiomyopathy: A randomized, double-blind, placebo-controlled study

1994 • 318 citations

Pharmacology of carvedilol

2004 • 297 citations

Dose-response of chronic beta-blocker treatment in heart failure from either idiopathic dilated or ischemic cardiomyopathy. Bucindolol Investigators.

1994 • 280 citations

Beta-blockade with bucindolol in heart failure caused by ischemic versus idiopathic dilated cardiomyopathy.

1991 • 232 citations

Effects of long-term monotherapy with enalapril, metoprolol, and digoxin on the progression of left ventricular dysfunction and dilation in dogs with reduced ejection fraction.

1994 • 207 citations

Beneficial effects of metoprolol in heart failure associated with coronary artery disease: A randomized trial

1994 • 204 citations

Pathophysiologic and pharmacologic rationales for clinical management of chronic heart failure with beta-blocking agents

1993 • 154 citations

Ventricular dysfunction and necrosis produced by adrenochrome metabolite of epinephrine: Relation to pathogenesis of catecholamine cardiomyopathy

1981 • 132 citations

The Effect of Beta Adrenergic Blockade on Patterns of Urinary Sodium Excretion

1966 • 127 citations

Beta-adrenergic receptor regulation and left ventricular function in idiopathic dilated cardiomyopathy

1993 • 112 citations

Cardioprotective effects of carvedilol, a novel adrenoceptor antagonist with vasodilating properties, in anaesthetised minipigs: comparison with propranolol

1992 • 81 citations

Preface

1991 • 3 citations