A Transient, EMT-Linked Loss of Basement Membranes Indicates Metastasis and Poor Survival in Colorectal Cancer

Epithelial–mesenchymal transitions in tumour progression

2002 • 6,431 citations

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

2004 • 3,727 citations

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

2000 • 3,504 citations

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

2000 • 2,569 citations

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

2001 • 1,351 citations

Migrating cancer stem cells — an integrated concept of malignant tumour progression

2005 • 1,323 citations

The transcription factor Slug repressesE-cadherinexpression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

2002 • 1,078 citations

Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

2001 • 1,020 citations

Snail blocks the cell cycle and confers resistance to cell death

2004 • 835 citations

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

2005 • 771 citations

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis

2003 • 679 citations

Invasion and Metastasis in Colorectal Cancer: Epithelial-Mesenchymal Transition, Mesenchymal-Epithelial Transition, Stem Cells and β-Catenin

2005 • 497 citations

Loss of basement membrane components by invasive tumors but not by their benign counterparts.

1983 • 497 citations

A New Role for E12/E47 in the Repression ofE-cadherin Expression and Epithelial-Mesenchymal Transitions

2001 • 439 citations

Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas.

1995 • 383 citations

Tumor Necrosis Factor-α Stimulates the Epithelial-to-Mesenchymal Transition of Human Colonic Organoids

2003 • 326 citations

The prognostic inhomogeneity in pT3 rectal carcinomas

2001 • 306 citations

Targeted Disruption of the LAMA3 Gene in Mice Reveals Abnormalities in Survival and Late Stage Differentiation of Epithelial Cells

1999 • 302 citations

Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution

2003 • 295 citations

The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation Program

2005 • 244 citations

The Invasion Front of Human Colorectal Adenocarcinomas Shows Co-Localization of Nuclear β-Catenin, Cyclin D1, and p16INK4A and Is a Region of Low Proliferation

2001 • 215 citations

Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin.

2001 • 180 citations

Differential expression of laminin-5 subunits and integrin receptors in human colorectal neoplasia

1998 • 169 citations

ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation

1997 • 147 citations

β-Catenin and TGFβ signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition

2004 • 145 citations

Down-Regulation of the Homeodomain Factor Cdx2 in Colorectal Cancer by Collagen Type I

2004 • 130 citations

Laminin-5 in the progression of carcinomas

2001 • 127 citations

Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment

2000 • 74 citations

Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB

1999 • 51 citations

Basal lamina formation by epithelial cell lines correlates with laminin A chain synthesis and secretion

1992 • 33 citations

Binding of USF to a non-canonical E-box following stress results in a cell-specific derepression of the lama3 gene

2002 • 29 citations

In situ-RT-PCR and immunohistochemistry for the localisation of the mRNA of the alpha 3 chain of laminin and laminin-5 during human organogenesis

2002 • 19 citations