The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation Program
Data up to Jan 2025
Total Citations Per Year
Abstract
References (25)
Epithelial–mesenchymal transitions in tumour progression
2002 • 6,431 citations
The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
2000 • 3,504 citations
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
2000 • 2,569 citations
The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells
2002 • 1,984 citations
The snail superfamily of zinc-finger transcription factors
2002 • 1,665 citations
The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion
2001 • 1,351 citations
Klf4 is a transcription factor required for establishing the barrier function of the skin
1999 • 763 citations
Regulation of tight junctions during the epithelium-mesenchyme transition:direct repression of the gene expression of claudins/occludin by Snail
2003 • 635 citations
Snail Induction of Epithelial to Mesenchymal Transition in Tumor Cells Is Accompanied by MUC1 Repression andZEB1 Expression
2002 • 467 citations
The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation
2004 • 312 citations
Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer.
2003 • 292 citations
NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins
1998 • 252 citations
Regulation of Vesicle Trafficking in Madin-Darby Canine Kidney Cells by Rab11a and Rab25
2000 • 226 citations
Unraveling signalling cascades for the Snail family of transcription factors
2004 • 225 citations
Protein Binding and Functional Characterization of Plakophilin 2
2002 • 223 citations
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.
2002 • 207 citations
Transcriptional Profiling of Krüppel-like Factor 4 Reveals a Function in Cell Cycle Regulation and Epithelial Differentiation
2003 • 199 citations
Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: steps towards invasiveness
2002 • 184 citations
EPLIN regulates actin dynamics by cross-linking and stabilizing filaments
2003 • 166 citations
Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality
2000 • 162 citations
GATA-4 and MEF2C transcription factors control the tissue-specific expression of the T-catenin gene CTNNA3
2004 • 51 citations
Gene profiling of hippocampal neuronal culture
2003 • 41 citations
Rise and Fall of Epithelial Phenotype
2005 • 40 citations
Normal retinal development and retinofugal projections in mice lacking the retina-specific variant of actin-binding lim domain protein
2003 • 16 citations
Epithelial Cell Plasticity by Dynamic Transcriptional Regulation of E-Cadherin
2005 • 4 citations