Snail blocks the cell cycle and confers resistance to cell death

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Epithelial–mesenchymal transitions in tumour progression

2002 • 6,431 citations

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

2000 • 3,504 citations

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

2000 • 2,569 citations

The snail superfamily of zinc-finger transcription factors

2002 • 1,665 citations

Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer

2003 • 1,572 citations

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

1995 • 1,060 citations

Cyclin D-dependent kinases, INK4 inhibitors and cancer

2002 • 770 citations

Control of Cell Behavior During Vertebrate Development by Slug , a Zinc Finger Gene

1994 • 744 citations

Peritoneal Dialysis and Epithelial-to-Mesenchymal Transition of Mesothelial Cells

2003 • 743 citations

Regulation of tight junctions during the epithelium-mesenchyme transition:direct repression of the gene expression of claudins/occludin by Snail

2003 • 635 citations

TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice

1996 • 619 citations

Transforming Growth Factor β-1 Induces Snail Transcription Factor in Epithelial Cell Lines

2003 • 617 citations

The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition

2001 • 611 citations

Chapter 11 In Situ Hybridization Analysis of Chick Embryos in Whole Mount and Tissue Sections

1996 • 584 citations

Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

2002 • 577 citations

Differential Expression of the Epithelial-Mesenchymal Transition Regulators Snail, SIP1, and Twist in Gastric Cancer

2002 • 573 citations

Mitotic domains reveal early commitment of cells in Drosophila embryos

1989 • 554 citations

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27

1999 • 497 citations

The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

1994 • 486 citations

Snail Induction of Epithelial to Mesenchymal Transition in Tumor Cells Is Accompanied by MUC1 Repression andZEB1 Expression

2002 • 467 citations

Phosphorylation of serine 10 in histone H3, what for?

2003 • 461 citations

Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo

1998 • 295 citations

Dorsalization of the neural tube by the non-neural ectoderm

1995 • 295 citations

Raf induces TGFβ production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

2000 • 292 citations

Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene

2001 • 223 citations

SnailprecedesSlugin the genetic cascade required for the specification and migration of theXenopusneural crest

2003 • 221 citations

The Invasion Front of Human Colorectal Adenocarcinomas Shows Co-Localization of Nuclear β-Catenin, Cyclin D1, and p16INK4A and Is a Region of Low Proliferation

2001 • 215 citations

Overexpression of Snail family members highlights their ability to promote chick neural crest formation

2002 • 211 citations

SLUG, a ces-1-Related Zinc Finger Transcription Factor Gene with Antiapoptotic Activity, Is a Downstream Target of the E2A-HLF Oncoprotein

1999 • 207 citations

The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.

2002 • 207 citations

Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas

2003 • 195 citations

Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo

2002 • 191 citations

Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: steps towards invasiveness

2002 • 184 citations

Slug is an Essential Target of TGFβ2 Signaling in the Developing Chicken Heart

2000 • 180 citations

Cloning and developmental expression of Sna, a murine homologue of the Drosophila snail gene

1992 • 178 citations

A rapid and non‐invasive selection of transgenic embryos before implantation using green fluorescent protein (GFP)

1995 • 171 citations

Transcriptional repressor snail and progression of human hepatocellular carcinoma.

2003 • 170 citations

Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development

1992 • 144 citations

Association between the Cell Cycle and Neural Crest Delamination through Specific Regulation of G1/S Transition

2002 • 142 citations

Signalling between the hindbrain and paraxial tissues dictates neural crest migration pathways

2002 • 141 citations

Neural Crest Apoptosis and the Establishment of Craniofacial Pattern: An Honorable Death

1996 • 134 citations

The C. elegans Cell Death Specification Gene ces-1 Encodes a Snail Family Zinc Finger Protein

1999 • 125 citations

Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor β in rat fetal hepatocytes

2001 • 117 citations

The Snail-like CES-1 protein of C. elegans can block the expression of theBH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins

2003 • 114 citations

Stat5 and Sp1 Regulate Transcription of the Cyclin D2 Gene in Response to IL-2

2001 • 112 citations

Modularity and reshuffling of Snail and Slug expression during vertebrate evolution

2002 • 110 citations

The increasing complexity of the Snail gene superfamily in metazoan evolution

2001 • 110 citations

The WNT antagonist cSFRP2 modulates programmed cell death in the developing hindbrain

2000 • 95 citations

Definition of the DNA-binding site repertoire for theDrosophilatranscription factor SNAIL

1993 • 93 citations

The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug

2003 • 87 citations

BMP signaling positively regulates Nodal expression during left right specification in the chick embryo

2002 • 74 citations

Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo

1998 • 71 citations

Inhibition of MMH (Met murine hepatocyte) cell differentiation by TGFβ is abrogated by pre-treatment with the heritable differentiation effector FGF1

2000 • 64 citations

Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes

2003 • 58 citations

Relationship between cell migration and cell cycle during the initiation of epithelial to fibroblastoid transition

1999 • 41 citations

ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2

2003 • 40 citations

Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells

2003 • 39 citations

Lymphocyte migration through extracellular matrix.

1992 • 32 citations

Cell‐cycle‐dependent invasion in vitro by rat ascites hepatoma cells

1995 • 27 citations

Apoptosis of Premigratory Neural Crest Cells in Rhombomeres 3 and 5: Consequences for Patterning of the Branchial Region

2002 • 27 citations

Relationship between cell migration and cell cycle during the initiation of epithelial to fibroblastoid transition

1999 • 4 citations