Expression of Adhesion Molecules and Histocompatibility Antigens at the Blood‐Brain Barrier

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

1986 • 2,490 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

1988 • 1,371 citations

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

Cellular immune reactivity within the CNS

1986 • 771 citations

A tissue-specific endothelial cell molecule involved in lymphocyte homing

1988 • 725 citations

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

1989 • 692 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Adhesion molecules controlling lymphocyte migration

1989 • 654 citations

Regulated expression and binding of three VLA (β1) integrin receptors on T cells

1990 • 634 citations

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization.

1989 • 627 citations

The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions.

1983 • 583 citations

CD44 — A molecule involved in leukocyte adherence and T-cell activation

1989 • 559 citations

Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells.

1987 • 554 citations

Cytokines as communication signals between leukocytes and endothelial cells

1989 • 528 citations

The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit.

1987 • 512 citations

Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils.

1990 • 478 citations

Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule.

1990 • 447 citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

1985 • 440 citations

Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones

1986 • 437 citations

Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes. A CD11/CD18-independent adhesion mechanism.

1990 • 408 citations

Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system.

1990 • 388 citations

P-24: a human leukemia-associated and lymphohemopoietic progenitor cell surface structure identified with monoclonal antibody.

1981 • 371 citations

The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis.

1990 • 367 citations

Adhesive protein receptors on hematopoietic cells

1988 • 350 citations

Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes.

1989 • 339 citations

Dual role of the CD44 molecule in T cell adhesion and activation.

1989 • 335 citations

Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types.

1989 • 327 citations

CD44 contributes to T cell activation.

1989 • 324 citations

A Distinct Endothelial Cell Recognition System That Controls Lymphocyte Traffic into Inflamed Synovium

1986 • 317 citations

Interleukin 1 increases the binding of human B and T lymphocytes to endothelial cell monolayers.

1986 • 296 citations

Interleukin-1 activation of vascular endothelium. Effects on procoagulant activity and leukocyte adhesion.

1985 • 295 citations

Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1983 • 295 citations

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex.

1989 • 291 citations

The Regulation of Lymphocyte Traffic

1986 • 285 citations

The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognition

1989 • 269 citations

Homing Receptors and the Control of Lymphocyte Migration

1986 • 265 citations

Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion.

1987 • 259 citations

Intrathecal application of interferon gamma. Progressive appearance of MHC antigens within the rat nervous system.

1990 • 240 citations

Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.

1990 • 230 citations

IL-4 increases human endothelial cell adhesiveness for T cells but not for neutrophils.

1990 • 217 citations

The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis

1986 • 214 citations

Microglial cells are a component of the perivascular glia limitans

1991 • 203 citations

Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis.

1990 • 199 citations

Stimulation of endothelial cell binding of lymphocytes by tumor necrosis factor.

1987 • 197 citations

Monoclonal antibody to a human brain‐granulocyte‐T lymphocyte antigen probably homologous to the W 3/13 antigen of the rat

1980 • 184 citations

Expression of Ia antigens by cultured astrocytes treated with gamma-interferon

1983 • 182 citations

Specific Cell-Adhesion Mechanisms Determining Migration Pathways of Recirculating Lymphocytes

1987 • 181 citations

Antigen presentation in the murine T-lymphocyte proliferative response. I. Requirement for genetic identity at the major histocompatibility complex

1977 • 160 citations

Rapid induction of neutrophil–endothelial adhesion by endothelial complement fixation

1989 • 150 citations

Endothelial cells augment T cell interleukin 2 production by a contact-dependent mechanism involving CD2/LFA-3 interaction.

1990 • 143 citations

Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro.

1990 • 140 citations

Fibronectin in multiple sclerosis lesions.

1989 • 132 citations

Lymphocyte migration into brain modelled in vitro: Control by lymphocyte activation, cytokines, and antigen

1990 • 126 citations

Triggering of co-mitogenic signals in T cell proliferation by anti-LFA-1 (CD18, CD11a), LFA-3, and CD7 monoclonal antibodies.

1988 • 121 citations

The lymphocyte function-associated antigen (LFA)-1 and CD2/LFA-3 pathways of antigen-independent human T cell adhesion.

1987 • 112 citations

Lymphoid tissue- and inflammation-specific endothelial cell differentiation defined by monoclonal antibodies.

1987 • 110 citations

Interaction of target cell-bound C3bi and C3d with human lymphocyte receptors. Enhancement of antibody-mediated cellular cytotoxicity.

1981 • 109 citations

Intercellular adhesion molecule-1 (ICAM-1) expression correlated to inflammation

1989 • 108 citations

Anti-CD9 monoclonal antibodies induce homotypic adhesion of pre-B cell lines by a novel mechanism.

1990 • 97 citations

Chemical composition and tissue distribution of the human CDw44 glycoprotein.

1989 • 95 citations

Effects of six different cytokines on lymphocyte adherence to microvascular endothelium and in vivo lymphocyte migration in the rat.

1990 • 94 citations

PSYCHONEUROIMMUNOLOGY

1991 • 90 citations

INFLAMMATION-INDUCED ENDOTHELIAL CELL ADHESION TO LYMPHOCYTES, NEUTROPHILS, AND MONOCYTES

1989 • 84 citations

Preliminary studies of cytokine-induced functional effects on the visual pathways in the rabbit

1989 • 72 citations

Activation of rat T lymphocytes by anti-CD2 monoclonal antibodies.

1988 • 67 citations

Differential central nervous system responses folloqing single and multiple recombinant interleukin-2 infusions

1990 • 51 citations

Human brain microvascular DR‐antigen

1989 • 48 citations

Stimulation of lymphocyte migration by endotoxin, tumor necrosis factor, and interferon

1989 • 46 citations

Antigen presentation in brain: brain endothelial cells are poor stimulators of T-cell proliferation.

1989 • 46 citations

Leukocyte membrane adhesion proteins LFA-1, CR3 and p150,95: A review of functional and regulatory aspects

1989 • 46 citations

Immunostaining of human brain capillaries by antibodies to very late antigens

1990 • 37 citations

The Immunopathology of Acute Experimental Allergic Encephalomyelitis. IV. An Ultrastructural Immunocytochemical Study of Class II Major Histocompatibility Complex Molecule (Ia) Expression

1987 • 36 citations

The acute inflammatory reaction

1989 • 30 citations

Expression of lymphocyte adhesion receptors for high endothelium in primates. Anatomic partitioning and linkage to activation.

1989 • 28 citations

Differential expression of guinea pig class II major histocompatibility complex antigens on vascular endothelial cells in vitro and in experimental allergic encephalomyelitis

1989 • 25 citations

Complement-derived polypeptide C3adesArg as a mediator of inflammation at the blood-brain barrier in a new experimental cat model

1989 • 23 citations

The immunopathology of acute experimental allergic encephalomyelitis. V. A light microscopic and ultrastructural immunohistochemical analysis of fibronectin and fibrinogen.

1988 • 19 citations

Monoclonal antibody 14E identifies the oligodendrocyte cell body in normal adult human and rat white matter

1988 • 13 citations