Antigen presentation in brain: brain endothelial cells are poor stimulators of T-cell proliferation.

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

Macrophages and microglia in the nervous system

1988 • 742 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain.

1981 • 589 citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

1985 • 440 citations

Human lymphocyte metabolism. Effects of cyclic and noncyclic nucleotides on stimulation by phytohemagglutinin

1971 • 393 citations

MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by γ-interferon

1987 • 346 citations

Interleukin 2-activated human lymphocytes exhibit enhanced adhesion to normal vascular endothelial cells and cause their lysis.

1987 • 219 citations

Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology.

1986 • 204 citations

The Purification and Characterization of Rat Gamma Interferon by Use of Two Monoclonal Antibodies

1986 • 204 citations

Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system.

1987 • 182 citations

Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis.

1987 • 163 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

Adhesion of lymphocytes to cerebral microvascular cells: effects of interferon-gamma, tumour necrosis factor and interleukin-1.

1988 • 119 citations

Antigen presentation in brain: MHC induction on brain endothelium and astrocytes compared.

1987 • 115 citations

Expression of I-region-associated antigen (Ia) and interleukin 1 by subcultured human endothelial cells

1985 • 72 citations

Interactions of T Lymphocytes with Human Vascular Endothelial Cells: Role of Endothelial Cells Surface Antigens

1984 • 66 citations

Brain capillary endothelial cells in vitro lack surface IgG Fc receptors

1986 • 53 citations

Evidence for antigen presentation in situ by endothelial cells and astrocytes

1985 • 50 citations

Cytolytic activity of antigen-specific T cells with helper phenotype.

1986 • 50 citations

Use of isolated brain capillaries and cultured endothelial cells to study the blood-brain barrier.

1984 • 46 citations

The endothelium ? Astrocyte immune control system of the brain

1985 • 44 citations

Synergy between interferons and monokines in MHC induction on brain endothelium

1988 • 37 citations

Ultracytochemical distribution of myelin basic protein after injection into the cerebrospinal fluid

1984 • 36 citations