Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system.

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

1986 • 2,490 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule.

1983 • 888 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

1982 • 740 citations

Treatment of multiple sclerosis with gamma interferon

1987 • 739 citations

Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

1988 • 680 citations

Adhesion molecules controlling lymphocyte migration

1989 • 654 citations

Warner-Lambert/Parke-Davis award lecture. Cytokine-mediated activation of vascular endothelium. Physiology and pathology.

1988 • 597 citations

Induction of intercellular adhesion molecule 1 on primary and continuous cell lines by pro-inflammatory cytokines. Regulation by pharmacologic agents and neutralizing antibodies.

1988 • 569 citations

Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells

1989 • 389 citations

The function of human intercellular adhesion molecule‐1 (ICAM‐1) in the generation of an immune response

1988 • 351 citations

Homing Receptors and Vascular Addressins: Cell Adhesion Molecules that Direct Lymphocyte Traffic

1989 • 332 citations

Functional evidence that intercellular adhesion molecule‐1 (icam‐1) is a ligand for lfa‐1d‐ependent adhesion in t cell‐mediated cytotoxicity

1988 • 322 citations

Intercellular adhesion molecule 1 (ICAM-1) has a central role in cell-cell contact-mediated immune mechanisms.

1988 • 312 citations

Microglia are the major cell type expressing MHC class II in human white matter

1987 • 302 citations

Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation.

1986 • 298 citations

T lymphocyte adhesion to endothelial cells: mechanisms demonstrated by anti-LFA-1 monoclonal antibodies.

1986 • 246 citations

On the presence of Ia-positive endothelial cells and astrocytes in multiple sclerosis lesions and its relevance to antigen presentation

1985 • 241 citations

The induction of intercellular adhesion molecule 1 (ICAM-1) expression on human fetal astrocytes by interferon-λ, tumor necrosis factor α, lymphotoxin, and interleukin-1: relevance to intracerebral antigen presentation

1989 • 227 citations

Endothelial activation during interleukin 2 immunotherapy. A possible mechanism for the vascular leak syndrome.

1988 • 225 citations

The immunopathology of experimental allergic encephalomyelitis. II. Endothelial cell Ia increases prior to inflammatory cell infiltration.

1984 • 198 citations

Mechanisms of lymphocyte adhesion to human vascular endothelial cells in culture. T lymphocyte adhesion to endothelial cells through endothelial HLA-DR antigens induced by gamma interferon.

1986 • 180 citations

pl50/95, Third member of the LFA‐1/CR₃ polypeptide family identified by anti‐Leu M5 monoclonal antibody

1985 • 149 citations

T cell adhesion molecules

1988 • 145 citations

Fibronectin in multiple sclerosis lesions.

1989 • 132 citations

IL-1 and IFN-gamma increase vascular permeability.

1988 • 131 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

Adhesion of lymphocytes to cerebral microvascular cells: effects of interferon-gamma, tumour necrosis factor and interleukin-1.

1988 • 119 citations

Antigen presentation in brain: MHC induction on brain endothelium and astrocytes compared.

1987 • 115 citations

The lymphocyte function-associated antigen (LFA)-1 and CD2/LFA-3 pathways of antigen-independent human T cell adhesion.

1987 • 112 citations

The immunopathology of experimental allergic encephalomyelitis. I. Quantitative analysis of inflammatory cells in situ.

1984 • 111 citations

Differential function of LFA-1 family molecules (CD11 and CD18) in adhesion of human monocytes to melanoma and endothelial cells.

1987 • 86 citations

The 2H4 (CD45R) antigen is selectively decreased in multiple sclerosis lesions.

1988 • 82 citations

The ultrastructural localization of von Willebrand factor in endothelial cells.

1984 • 79 citations

Differential role of distinct determinants of intercellular adhesion molecule-1 in immunologic phenomena.

1989 • 79 citations

Cell surface endothelial proteins altered in experimental allergic encephalomyelitis

1989 • 77 citations

Immune response gene products (Ia antigens) on glial and endothelial cells in virus-induced demyelination.

1987 • 67 citations

Migration of lymphocytes through endothelial cell monolayers: Augmentation by interferon-γ

1988 • 66 citations

Major Histocompatibility.Complex Molecule Expression in the Human Central Nervous System: Immunohistochemical Analysis of 40 Patients

1988 • 65 citations

MACROPHAGE POPULATIONS ASSOCIATED WITH MULTIPLE SCLEROSIS PLAQUES

1987 • 63 citations

Monoclonal antibodies to guinea pig Ia antigens. II. Effect on alloantigen-, antigen-, and mitogen-induced T lymphocyte proliferation in vitro.

1980 • 61 citations

Cultured human endothelial cells stimulated with cytokines or endotoxin produce an inhibitor of leukocyte adhesion.

1988 • 58 citations

The in situ cellular immune response in acute herpes simplex encephalitis.

1986 • 56 citations

Production and characterization of monoclonal antibodies to guinea pig lymphoid differentiation antigens

1983 • 28 citations

Leukocyte adhesion molecules involved in inflammation.

1989 • 19 citations

T-lymphocyte subsets in the multiple sclerosis lesion

1989 • 17 citations

Multiple sclerosis as autoimmune disease: Vascular antigens

1989 • 5 citations