Shigella Phagocytic Vacuolar Membrane Remnants Participate in the Cellular Response to Pathogen Invasion and Are Regulated by Autophagy

Pathogen Recognition and Innate Immunity

2006 • 11,197 citations

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

2007 • 4,197 citations

Self-eating and self-killing: crosstalk between autophagy and apoptosis

2007 • 3,403 citations

The role of autophagy during the early neonatal starvation period

2004 • 2,753 citations

Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice

2007 • 2,035 citations

Autophagy: from phenomenology to molecular understanding in less than a decade

2007 • 1,866 citations

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

2003 • 1,102 citations

A TECHNIQUE FOR ULTRACRYOTOMY OF CELL SUSPENSIONS AND TISSUES

1973 • 1,057 citations

The type III secretion injectisome

2006 • 1,021 citations

Unveiling the roles of autophagy in innate and adaptive immunity

2007 • 861 citations

Escape of Intracellular Shigella from Autophagy

2004 • 798 citations

Involvement of a plasmid in the invasive ability of Shigella flexneri

1982 • 733 citations

CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri

2001 • 588 citations

Caspases in cell survival, proliferation and differentiation

2006 • 553 citations

Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages

2007 • 525 citations

Caspase-1 Activation of Lipid Metabolic Pathways in Response to Bacterial Pore-Forming Toxins Promotes Cell Survival

2006 • 497 citations

An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

2008 • 482 citations

The atypical PKC-interacting protein p62 channels NF-kappa B activation by the IL-1-TRAF6 pathway

2000 • 422 citations

Shigella-induced Apoptosis Is Dependent on Caspase-1 Which Binds to IpaB

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Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation

2006 • 353 citations

Constitutive Activation of Chaperone-mediated Autophagy in Cells with Impaired Macroautophagy

2008 • 318 citations

Signal integration and diversification through the p62 scaffold protein

2006 • 314 citations

p62/SQSTM1: A Missing Link between Protein Aggregates and the Autophagy Machinery

2005 • 298 citations

Microbial Pathogen-Induced Necrotic Cell Death Mediated by the Inflammasome Components CIAS1/Cryopyrin/NLRP3 and ASC

2007 • 289 citations

Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction

2002 • 239 citations

Shigella’s ways of manipulating the host intestinal innate and adaptive immune system: a tool box for survival?

2007 • 225 citations

Differential sorting and fate of endocytosed GPI-anchored proteins

2002 • 221 citations

The p62 Scaffold Regulates Nerve Growth Factor-induced NF-κB Activation by Influencing TRAF6 Polyubiquitination

2005 • 211 citations

Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination

2007 • 184 citations

icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread

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Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells.

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Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes

2007 • 164 citations

Cholesterol binding by the bacterial type III translocon is essential for virulence effector delivery into mammalian cells

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The versatility of Shigella effectors

2007 • 160 citations

Rupture, invasion and inflammatory destruction of the intestinal barrier byShigella, making sense of prokaryote–eukaryote cross-talks

2001 • 153 citations

Shigella Induces Mitochondrial Dysfunction and Cell Death in Nonmyleoid Cells

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Innate recognition of intracellular bacteria

2006 • 150 citations

CD44 binds to the Shigella IpaB protein and participates in bacterial invasion of epithelial cells

2000 • 143 citations

Caspase-1 Contributes toChlamydia trachomatis-Induced Upper Urogenital Tract Inflammatory Pathologies without Affecting the Course of Infection

2007 • 132 citations

Induction of anti‐carbohydrate antibodies by phage library‐selected peptide mimics

1997 • 113 citations

Chlamydia trachomatis Infection of Epithelial Cells Induces the Activation of Caspase-1 and Release of Mature IL-18

2000 • 107 citations

Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling

2001 • 106 citations

Sensing of bacteria: NOD a lonely job

2006 • 105 citations

Rafts Can Trigger Contact-mediated Secretion of Bacterial Effectors via a Lipid-based Mechanism

2004 • 86 citations

Analysis of epithelial cell stress response during infection by Shigella flexneri

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Rupture, invasion and inflammatory destruction of the intestinal barrier by Shigella, making sense of prokaryote–eukaryote cross-talks

2001 • 72 citations

Shigella flexneri Inhibits Staurosporine-Induced Apoptosis in Epithelial Cells

2007 • 61 citations

Ubiquitin: tool and target for intracellular NF-κB inhibitors

2006 • 61 citations

TRAF6 Regulates Cell Fate Decisions by Inducing Caspase 8-dependent Apoptosis and the Activation of NF-κB

2006 • 44 citations

A role for Nod-like receptors in autophagy induced byShigellainfection

2008 • 41 citations