CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling

1997 • 1,159 citations

Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors

2000 • 754 citations

Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB

1999 • 725 citations

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants

1998 • 573 citations

Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1997 • 552 citations

An Induced Proximity Model for NF-κB Activation in the Nod1/RICK and RIP Signaling Pathways

2000 • 535 citations

Human Nod1 Confers Responsiveness to Bacterial Lipopolysaccharides

2001 • 534 citations

Transcriptional regulation in the immune system: all roads lead to AP-1

1998 • 388 citations

Human CARD4 Protein Is a Novel CED-4/Apaf-1 Cell Death Family Member That Activates NF-κB

1999 • 363 citations

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

1998 • 316 citations

InvasiveShigella flexneriActivates NF-κB Through a Lipopolysaccharide-Dependent Innate Intracellular Response and Leads to IL-8 Expression in Epithelial Cells

2000 • 249 citations

Mutant Cells That Do Not Respond to Interleukin-1 (IL-1) Reveal a Novel Role for IL-1 Receptor-Associated Kinase

1999 • 227 citations

The PYRIN domain: a novel motif found in apoptosis and inflammation proteins

2000 • 180 citations

Stress-activated protein kinases are negatively regulated by cell density

1998 • 92 citations

A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation

2001 • 64 citations