Endoplasmic Reticulum-Mediated Phagocytosis Is a Mechanism of Entry into Macrophages

MECHANISMS OF PHAGOCYTOSIS IN MACROPHAGES

1999 • 2,766 citations

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1982 • 1,313 citations

C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

2001 • 1,122 citations

Identification of Two Distinct Mechanisms of Phagocytosis Controlled by Different Rho GTPases

1998 • 993 citations

The Phosphatidylinositol 3‐Kinase Inhibitors Wortmannin and LY294002 Inhibit Autophagy in Isolated Rat Hepatocytes

1997 • 828 citations

Phagocytosis and the actin cytoskeleton

2001 • 689 citations

The Phagosome Proteome

2001 • 680 citations

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1994 • 676 citations

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

1983 • 644 citations

Association of folding intermediates of glycoproteins with calnexin during protein maturation

1993 • 558 citations

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1995 • 556 citations

Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis

2000 • 537 citations

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

2001 • 531 citations

Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion

2001 • 513 citations

Dissection of the Golgi complex. I. Monensin inhibits the transport of viral membrane proteins from medial to trans Golgi cisternae in baby hamster kidney cells infected with Semliki Forest virus.

1983 • 430 citations

A Requirement for Phosphatidylinositol 3-Kinase in Pseudopod Extension

1999 • 414 citations

Brucella abortus Transits through the Autophagic Pathway and Replicates in the Endoplasmic Reticulum of Nonprofessional Phagocytes

1998 • 408 citations

Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells

1992 • 393 citations

The ins and outs of calreticulin: from the ER lumen to the extracellular space

2001 • 335 citations

How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: implications for conversion of plasma membrane to the ER membrane

2001 • 329 citations

Biogenesis of Salmonella typhimurium-containing vacuoles in epithelial cells involves interactions with the early endocytic pathway

1999 • 328 citations

Flotillin-1-enriched Lipid Raft Domains Accumulate on Maturing Phagosomes

2001 • 305 citations

Molecular characterization of phagosomes.

1994 • 287 citations

The macrophage capacity for phagocytosis

1992 • 273 citations

Fc receptor-mediated phagocytosis requires CDC42 and Rac1

1998 • 254 citations

Biogenesis of phagolysosomes: the 'kiss and run' hypothesis

1995 • 252 citations

Raft association of SNAP receptors acting in apical trafficking in Madin–Darby canine kidney cells

1999 • 242 citations

Controlling the maturation of pathogen-containing vacuoles: a matter of life and death

1999 • 241 citations

Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis

2001 • 231 citations

Alterations in the protein composition of maturing phagosomes.

1992 • 205 citations

Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages

2000 • 180 citations

Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes

1999 • 161 citations

Intracellular Survival ofLeishmania majorin Neutrophil Granulocytes after Uptake in the Absence of Heat-Labile Serum Factors

2002 • 160 citations

v-SNARE-dependent secretion is required for phagocytosis

1998 • 149 citations

Dynamics of Cytoskeletal Proteins during Fcγ Receptor-mediated Phagocytosis in Macrophages

2002 • 143 citations

Maturation of phagosomes is accompanied by changes in their fusion properties and size-selective acquisition of solute materials from endosomes

1997 • 130 citations

In Vitro Fusion of Phagosomes with Different Endocytic Organelles from J774 Macrophages

1998 • 127 citations

Cell Surface Expression of Calnexin, a Molecular Chaperone in the Endoplasmic Reticulum

2000 • 126 citations

Antigen Loading of MHC Class I Molecules in the Endocytic Tract

2001 • 108 citations

Ultrastructural morphometric analysis of Brucella abortus-infected trophoblasts in experimental placentitis. Bacterial replication occurs in rough endoplasmic reticulum.

1986 • 103 citations

Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assemblyin vitro

2000 • 89 citations

Protein folding in a specialized compartment: the endoplasmic reticulum

1999 • 78 citations

Amphiphysin IIm, a Novel Amphiphysin II Isoform, Is Required for Macrophage Phagocytosis

2000 • 77 citations

Structures of the N-linked oligosaccharides of Gp63, the major surface glycoprotein, from Leishmania mexicana amazonensis.

1990 • 76 citations

Electron microscopic examination of the inflammatory response to Legionella pneumophila in guinea pigs.

1982 • 65 citations

Effects of bafilomycin A1 on functional capabilities of LPS-activated alveolar macrophages

1995 • 52 citations

A METHOD FOR THE ISOLATION OF PLASMA MEMBRANE OF ANIMAL CELLS

1971 • 46 citations

Localization of GTP-stimulated core glycosylation to fused microsomes.

1983 • 45 citations

BiP/GRP78-Induced Production of Cytokines and Uptake of Amyloid-β(1-42) Peptide in Microglia

2001 • 45 citations

Selectin Blockade Reduces Neutrophil Interaction With Platelets at the Site of Deep Arterial Injury by Angioplasty in Pigs

1999 • 39 citations

Resynthesis of phosphatidylinositol in permeabilized neutrophils following phospholipase Cβ activation: transport of the intermediate, phosphatidic acid, from the plasma membrane to the endoplasmic reticulum for phosphatidylinositol resynthesis is not dependent on soluble lipid carriers or vesicular transport

1999 • 36 citations

Lack of Fusion of Azurophil Granules with Phagosomes during Phagocytosis ofMycobacterium smegmatisby Human Neutrophils Is Not Actively Controlled by the Bacterium

2002 • 26 citations

Flow cytometric sorting and biochemical characterization of the late endosomal rab7‐containing compartment

1997 • 22 citations

Electrophoretic protein blots as aids in choosing fixatives for immunocytochemistry.

1988 • 14 citations

High-level bacterial expression, purification and characterization of human calreticulin

1991 • 13 citations

On the origin of the phagocytic membrane

1977 • 11 citations