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Common themes in microbial pathogenicity revisited

1997 • 1,370 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1998 • 1,101 citations

RESPONSE OF CULTURED MACROPHAGES TO MYCOBACTERIUM TUBERCULOSIS, WITH OBSERVATIONS ON FUSION OF LYSOSOMES WITH PHAGOSOMES

1971 • 973 citations

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

1993 • 896 citations

Common themes in microbial pathogenicity revisited.

1997 • 782 citations

EEA1, an Early Endosome-Associated Protein.

1995 • 706 citations

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

1983 • 704 citations

Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.

1995 • 680 citations

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1994 • 676 citations

Membrane transport in the endocytic pathway

1995 • 644 citations

Rab 7: an important regulator of late endocytic membrane traffic.

1995 • 625 citations

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1995 • 556 citations

Arrest of Mycobacterial Phagosome Maturation Is Caused by a Block in Vesicle Fusion between Stages Controlled by rab5 and rab7

1997 • 556 citations

THE LIPOPHOSPHOGLYCAN OF LEISHMANIA PARASITES

1992 • 473 citations

Toxoplasma gondii : Fusion Competence of Parasitophorous Vacuoles in Fc Receptor-Transfected Fibroblasts

1990 • 446 citations

Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

1984 • 384 citations

THE ROLE OF pH AND TEMPERATURE IN THE DEVELOPMENT OF LEISHMANIA PARASITES

1994 • 367 citations

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

1998 • 360 citations

Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages.

1994 • 358 citations

The Interaction of Leishmania Species with Macrophages

1992 • 323 citations

Double targeted gene replacement for creating null mutants.

1991 • 323 citations

Phagocytosis of the legionnaires' disease bacterium (legionella pneumophila) occurs by a novel mechanism: Engulfment within a Pseudopod coil

1984 • 317 citations

Role of the Small GTPase RAB7 in the Late Endocytic Pathway

1997 • 302 citations

The rab7 gtpase resides on a vesicular compartment connected to lysosomes

1995 • 297 citations

Phagosome acidification blocked by intracellular Toxoplasma gondii

1985 • 295 citations

Molecular characterization of phagosomes.

1994 • 287 citations

Inhibition of Phagolysosomal Biogenesis by the Leishmania Lipophosphoglycan

1997 • 281 citations

Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages.

1992 • 277 citations

Rapid isolation of DNA from trypanosomatid protozoa using a simple ‘mini-prep’ procedure

1993 • 275 citations

Multiplication of a Human Parasite ( Leishmania donovani ) in Phagolysosomes of Hamster Macrophages in Vitro

1976 • 274 citations

Fusion of Host Cell Secondary Lysosomes with the Parasitophorous Vacuoles ofLeishmania mexicana-inlected Macrophages

1975 • 266 citations

VirulentBrucella abortusPrevents Lysosome Fusion and Is Distributed within Autophagosome-Like Compartments

1998 • 256 citations

Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors.

1995 • 256 citations

Use of the green fluorescent protein as a marker in transfected Leishmania

1996 • 255 citations

Biogenesis of phagolysosomes: the 'kiss and run' hypothesis

1995 • 252 citations

Developmental changes in the glycosylated phosphatidylinositols of Leishmania donovani. Characterization of the promastigote and amastigote glycolipids

1991 • 235 citations

Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH

1990 • 234 citations

THE INTERACTION BETWEEN TOXOPLASMA GONDII AND MAMMALIAN CELLS

1972 • 228 citations

Evidence for inhibition of fusion of lysosomal and prelysosomal compartments with phagosomes in macrophages infected with pathogenic Mycobacterium avium

1986 • 223 citations

Evidence that the vectorial competence of phlebotomine sand flies for different species of Leishmania is controlled by structural polymorphisms in the surface lipophosphoglycan.

1994 • 208 citations

Alterations in the protein composition of maturing phagosomes.

1992 • 205 citations

Intracellular fate of vacuoles containing Toxoplasma gondii is determined at the time of formation and depends on the mechanism of entry.

1997 • 179 citations

Mycobacterium avium- and Mycobacterium tuberculosis-containing vacuoles are dynamic, fusion-competent vesicles that are accessible to glycosphingolipids from the host cell plasmalemma.

1996 • 178 citations

Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages

1992 • 168 citations

Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens.

1988 • 164 citations

A Specialized Pathway Affecting Virulence Glycoconjugates of Leishmania

1995 • 156 citations

Requirement of lipophosphoglycan for intracellular survival of Leishmania donovani within human monocytes.

1990 • 144 citations

The biogenesis of lysosomes: Is it a kiss and run, continuous fusion and fission process?

1996 • 144 citations

Fusion of newly formed phagosomes with endosomes in intact cells and in a cell-free system.

1991 • 141 citations

Phagocytic processing of the macrophage endoparasite, Mycobacterium avium, in comparison to phagosomes which contain Bacillus subtilis or latex beads.

1995 • 130 citations

Maturation of phagosomes is accompanied by changes in their fusion properties and size-selective acquisition of solute materials from endosomes

1997 • 130 citations

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages.

1986 • 127 citations

Identification of Legionella pneumophila mutants that have aberrant intracellular fates

1996 • 122 citations

Evidence for retrograde traffic between terminal lysosomes and the prelysosomal/late endosome compartment

1994 • 117 citations

The immunochemical structure and surface arrangement of Leishmania donovani lipophosphoglycan determined using monoclonal antibodies

1989 • 116 citations

Phagosome maturation and fusion with lysosomes in relation to surface property and size of the phagocytic particle.

1997 • 113 citations

How is the intracellular fate of the Legionella pneumophila phagosome determined?

1998 • 101 citations

Rab7 Regulates Transport from Early to Late Endocytic Compartments in Xenopus Oocytes

1997 • 99 citations

Intracellular fate of Mycobacterium leprae in normal and activated mouse macrophages

1987 • 92 citations

Leishmania donovani-infected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation

1994 • 86 citations

Deficiency in β1,3-Galactosyltransferase of a Leishmania major Lipophosphoglycan Mutant Adversely Influences the Leishmania-Sand Fly Interaction

1996 • 85 citations

Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani.

1996 • 79 citations

Expression of a repeating phosphorylated disaccharide lipophosphoglycan epitope on the surface of macrophages infected with Leishmania donovani

1990 • 78 citations

Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages.

1996 • 72 citations

Localization and activity of various lysosomal proteases in Leishmania amazonensis-infected macrophages

1990 • 69 citations

Analysis and isolation of endocytic vesicles by flow cytometry and sorting: demonstration of three kinetically distinct compartments involved in fluid-phase endocytosis.

1985 • 64 citations

Potent inhibition of viral fusion by the lipophosphoglycan of Leishmania donovani

1995 • 62 citations

The lipophosphoglycan of Leishmania and macrophage protein kinase C

1993 • 59 citations

Legionnaires' disease: the pore macrophage and the legion of terror within

1998 • 51 citations

Chapter 14: Isolation and Characterization of Pathogen-Containing Phagosomes

1995 • 50 citations

Receptor-mediated entry of beta-glucuronidase into the parasitophorous vacuoles of macrophages infected with Leishmania mexicana amazonensis.

1983 • 49 citations

Receptor-Mediated Entry of Peroxidases Into the Parasitophorous Vacuoles of Macrophages Infected With Leishmania Mexicana Amazonensis

1985 • 48 citations

The Lipophosphoglycan of Leishmania Parasites

1992 • 43 citations

The Role of pH and Temperature in the Development of Leishmania Parasites

1994 • 30 citations

Flow cytometric sorting and biochemical characterization of the late endosomal rab7‐containing compartment

1997 • 22 citations