Neurotrophins induce release of neurotrophins by the regulated secretory pathway

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

2013 • 3,921 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Neurotrophins and Neuronal Plasticity

1995 • 1,937 citations

Physiology of the Neurotrophins

1996 • 1,908 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

1995 • 1,416 citations

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

1995 • 1,354 citations

Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice

1996 • 1,219 citations

Requirement for BDNF in Activity-Dependent Survival of Cortical Neurons

1994 • 974 citations

CREB: A Major Mediator of Neuronal Neurotrophin Responses

1997 • 936 citations

Anterograde transport of brain-derived neurotrophic factor and its role in the brain

1997 • 853 citations

Functional Interactions of Neurotrophins and Neurotrophin Receptors

1995 • 825 citations

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75

1996 • 768 citations

The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons

1992 • 752 citations

A BDNF autocrine loop in adult sensory neurons prevents cell death

1995 • 743 citations

Signal transduction by the neutrophin receptors

1997 • 573 citations

Inhibition of Ocular Dominance Column Formation by Infusion of NT-4/5 or BDNF

1995 • 572 citations

Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

1992 • 564 citations

Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

1992 • 521 citations

Nerve Growth Factor Treatment Increases Brain-Derived Neurotrophic Factor Selectively in TrkA-Expressing Dorsal Root Ganglion Cells and in Their Central Terminations within the Spinal Cord

1997 • 500 citations

Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.

1996 • 390 citations

Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins

1995 • 381 citations

K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity.

1992 • 368 citations

Regulated Release and Polarized Localization of Brain-Derived Neurotrophic Factor in Hippocampal Neurons

1996 • 325 citations

Characterization of Nerve Growth Factor (NGF) Release from Hippocampal Neurons: Evidence for a Constitutive and an Unconventional Sodium‐dependent Regulated Pathway

1995 • 319 citations

Blockade of Endogenous Ligands of TrkB Inhibits Formation of Ocular Dominance Columns

1997 • 309 citations

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

1991 • 296 citations

Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N -methyl- <scp>d</scp> -aspartate receptor subunit 1

1997 • 286 citations

Anterograde transport of neurotrophins and axodendritic transfer in the developing visual system

1996 • 284 citations

Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons

1996 • 275 citations

Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene.

1991 • 272 citations

Neurotrophin release by neurotrophins: Implications for activity-dependent neuronal plasticity

1997 • 268 citations

Neurotrophic factors and synaptic plasticity

1995 • 259 citations

Nerve growth factor (NGF) prevents the shift in ocular dominance distribution of visual cortical neurons in monocularly deprived rats

1992 • 255 citations

The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines

1991 • 252 citations

Neurotrophins Induce Sphingomyelin Hydrolysis

1995 • 245 citations

TrkA cross-linking mimics neuronal responses to nerve growth factor.

1994 • 222 citations

Neurotrophins Live or Let Die: Does p75NTR Decide?

1997 • 211 citations

Neurotrophins Stimulate the Release of Dopamine from Rat Mesencephalic Neurons via Trk and p75Lntr Receptors

1996 • 187 citations

Potentiation of Developing Synapses by Postsynaptic Release of Neurotrophin-4

1997 • 176 citations

Retrograde Transport of Neurotrophins from the Eye to the Brain in Chick Embryos: Roles of the p75^NTRand trkB Receptors

1996 • 155 citations

Localization of Cellular Storage Compartments and Sites of Constitutive and Activity-Dependent Release of Nerve Growth Factor (NGF) in Primary Cultures of Hippocampal Neurons

1996 • 151 citations

K-252a and staurosporine selectively block autophosphorylation of neurotrophin receptors and neurotrophin-mediated responses.

1992 • 140 citations

Are Neurotrophins Synaptotrophins?

1996 • 134 citations

Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density

1996 • 112 citations

Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector.

1988 • 110 citations

The Regulated Secretion and Vectorial Targeting of Neurotrophins in Neuroendocrine and Epithelial Cells

1996 • 92 citations

Monoclonal antibodies to nerve growth factor affect the postnatal development of the visual system.

1994 • 90 citations

Brain-derived Neurotrophic Factor Binding to the p75 Neurotrophin Receptor Reduces TrkA Signaling While Increasing Serine Phosphorylation in the TrkA Intracellular Domain

1997 • 79 citations

Protein Targeting in the Neuron

1993 • 70 citations

Nerve growth factor in the anterior pituitary: localization in mammotroph cells and cosecretion with prolactin by a dopamine-regulated mechanism.

1996 • 69 citations

The Biosynthesis of Neurotrophin Heterodimers by Transfected Mammalian Cells

1995 • 67 citations

Activation of calcium-dependent potassium channels in rat brain neurons by neurotrophin-3 and nerve growth factor

1997 • 65 citations

Subcellular localization of epitope-tagged neurotrophins in neuroendocrine cells

1998 • 62 citations

Differential effects of the protein kinase inhibitor K-252a on the in vitro survival of chick embryonic neurons

1990 • 52 citations

trkA Mediates the Nerve Growth Factor-induced Intracellular Calcium Accumulation

1996 • 42 citations

Neurotrophin regulation of ionic currents and cell size depends on cell context

1997 • 32 citations

Processing and Secretion of Nerve Growth Factor: Expression in Mammalian Cells with a Vaccinia Virus Vector

1988 • 30 citations

Both p140 and p75NGFR Nerve Growth Factor Receptors Mediate Nerve Growth Factor-stimulated Calcium Uptake

1997 • 29 citations

The Role of the Nerve Growth Factor Carboxyl Terminus in Receptor Binding and Conformational Stability

1997 • 22 citations