Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

2013 • 3,921 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

Calcium Signaling in Neurons: Molecular Mechanisms and Cellular Consequences

1995 • 1,421 citations

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

1995 • 1,367 citations

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

1995 • 1,354 citations

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

1993 • 1,302 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

1983 • 1,162 citations

Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF

1993 • 753 citations

Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors.

1995 • 612 citations

MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B.

1989 • 550 citations

Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes.

1983 • 535 citations

Distinct pools of synaptic vesicles in neurotransmitter release

1995 • 526 citations

Stimulation of Protein Tyrosine Phosphorylation by NMDA Receptor Activation

1991 • 464 citations

A rapid method for isolation of synaptosomes on Percoll gradients

1986 • 421 citations

Synapsin I bundles F-actin in a phosphorylation-dependent manner

1987 • 409 citations

Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.

1995 • 333 citations

Regulation by synapsin I and Ca(2+)‐calmodulin‐dependent protein kinase II of the transmitter release in squid giant synapse.

1991 • 318 citations

Positive Feedback between Acetylcholine and the Neurotrophins Nerve Growth Factor and Brain‐derived Neurotrophic Factor in the Rat Hippocampus

1994 • 301 citations

Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice.

1995 • 244 citations

Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain.

1987 • 212 citations

BDNF and NT-3 induce intracellular Ca2+ elevation in hippocampal neurones

1993 • 197 citations

Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb

1991 • 179 citations

Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I.

1987 • 179 citations

Synapsin I: an actin-bundling protein under phosphorylation control.

1987 • 176 citations

Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals.

1989 • 169 citations

Interaction of free and synaptic vesicle-bound synapsin I with F-actin

1992 • 167 citations

Neurotrophin 3 potentiates neuronal activity and inhibits gamma-aminobutyratergic synaptic transmission in cortical neurons.

1994 • 164 citations

Dephosphorylated synapsin I anchors synaptic vesicles to actin cytoskeleton: an analysis by videomicroscopy.

1995 • 159 citations

Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses

1992 • 147 citations

Neurotrophin signalling

1994 • 142 citations

Purification and characterization of a maturation-activated myelin basic protein kinase from sea star oocytes.

1990 • 141 citations

The MAP Kinase Cascade

1995 • 135 citations

[23] Production of phosphorylation state-specific antibodies

1991 • 132 citations

Potentiation of Transmitter Release by Ciliary Neurotrophic Factor Requires Somatic Signaling

1995 • 128 citations

Short-term modulation of glutamatergic synapses in adult rat hippocampus by NGF

1994 • 112 citations

Depolarizing stimuli regulate nerve growth factor gene expression in cultured hippocampal neurons.

1991 • 111 citations

Aberrant Neurites and Synaptic Vesicle Protein Deficiency in Synapsin II-Depleted Neurons

1994 • 105 citations

Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture.

1995 • 96 citations

Signal transduction events mediated by the BDNF receptor gp 145trkB in primary hippocampal pyramidal cell culture

1993 • 90 citations

Map Kinases Erk1 And Erk2: Pleiotropic Enzymes In A Ubiquitous Signaling Network

1994 • 74 citations

Effects of the neuronal phosphoprotein synapsin I on actin polymerization. I. Evidence for a phosphorylation-dependent nucleating effect.

1992 • 73 citations

Networking with proline-directed protein kinases implicated in Tau phosphorylation

1995 • 60 citations

Phosphorylation of synapsin I at a novel site by proline-directed protein kinase.

1990 • 56 citations

A new method for the selective isolation of phosphoserine‐containing peptides

1987 • 49 citations

Synapsin I in PC12 cells. II. Evidence for regulation by NGF of phosphorylation at a novel site

1987 • 44 citations

Nicotinic Agonists, Phorbol Esters, and Growth Factors Activate Two Extracellular Signal‐Regulated Kinases, ERK1 and ERK2, in Bovine Chromaffin Cells

1992 • 23 citations