Real-time imaging of T-cell development

Two-Photon Laser Scanning Fluorescence Microscopy

1990 • 9,129 citations

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

2004 • 1,657 citations

Positive and Negative Selection of T Cells

2003 • 1,547 citations

Two-Photon Imaging of Lymphocyte Motility and Antigen Response in Intact Lymph Node

2002 • 1,177 citations

Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes

2003 • 599 citations

Two-photon tissue imaging: seeing the immune system in a fresh light

2002 • 482 citations

Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy

2003 • 480 citations

Dynamics of Thymocyte-Stromal Cell Interactions Visualized by Two-Photon Microscopy

2002 • 278 citations

Studies on T cell maturation on defined thymic stromal cell populations in vitro.

1992 • 249 citations

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate

2000 • 244 citations

Role for CCR7 Ligands in the Emigration of Newly Generated T Lymphocytes from the Neonatal Thymus

2002 • 218 citations

Chemokines in lymphopoiesis and lymphoid organ development

2001 • 187 citations

Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus

2003 • 186 citations

Imaging Synapse Formation during Thymocyte Selection

2002 • 142 citations

Immature CD4+CD8+ Thymocytes Form a Multifocal Immunological Synapse with Sustained Tyrosine Phosphorylation

2002 • 138 citations

Intrathymic T-cell migration: a combinatorial interplay of extracellular matrix and chemokines?

2002 • 137 citations

Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo

2004 • 111 citations

T-cell differentiation in thymus organ cultures.

1990 • 100 citations

Fetal thymic organ cultures

1994 • 79 citations

Thymocyte Sensitivity and Supramolecular Activation Cluster Formation Are Developmentally Regulated: A Partial Role for Sialylation

2003 • 57 citations

Characteristics of an in vitro system of thymocyte positive selection.

1994 • 51 citations

Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes

2003 • 39 citations

Modeling TCR Signaling Complex Formation in Positive Selection

2003 • 26 citations