Studies on T cell maturation on defined thymic stromal cell populations in vitro.

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1981 • 1,582 citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro.

1979 • 514 citations

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand

1989 • 386 citations

Kinetics of mature T-cell development in the thymus.

1990 • 331 citations

A Nondeletional Mechanism of Thymic Self Tolerance

1989 • 322 citations

Positive selection of the T cell repertoire: Where and when does it occur?

1989 • 242 citations

Developmental Status and Reconstitution Potential of Subpopulations of Murine Thymocytes

1988 • 211 citations

Antigen-induced apoptosis in developing t cells: a mechanism for negative selection of the t cell receptor repertoire*

1989 • 186 citations

Thymocyte subpopulations: an experimental review, including flow cytometric cross-correlations between the major murine thymocyte markers.

1983 • 178 citations

Cytokines in T-cell development

1991 • 164 citations

Positive selection of CD4+ T cells mediated by MHC class ll-bearing stromal cell in the thymic cortex

1989 • 130 citations

Requirement of dendritic cells and B cells in the clonal deletion of Mls-reactive T cells in the thymus.

1991 • 113 citations

Stromal cell types in the developing thymus of the normal and nude mouse embryo

1985 • 108 citations

T-cell differentiation in thymus organ cultures.

1990 • 100 citations

Dendritic cells of the mouse recognized by two monoclonal antibodies

1987 • 99 citations

Thymic cortical epithelial cells lack full capacity for antigen presentation

1989 • 85 citations

Alkaline phosphatase-fast red, a new fluorescent label

1990 • 70 citations

Thymic epithelial cells induce in vitro differentiation of PRO-T lymphocyte clones into TCR alpha,beta/T3+ and TCR gamma,delta/T3+ cells.

1989 • 43 citations

Differentiation of thymocytes from CD3-CD4-CD8- through CD3-CD4-CD8+ into more mature stages induced by a thymic stromal cell clone.

1990 • 43 citations

Intrathymic proliferation of perinatal mouse αβ and §γ T cell receptor-expressing mature T cells

1990 • 42 citations

Timing of deletion of autoreactive V _β6+ cells and down-modulation of either CD4 orCD8 on phenotypically distinct CD4+8+ subsets of thymocytes expressingintermediate or high levels of T cell receptor

1991 • 39 citations

Negative and positive selection of immature thymocytes: timing and the role of the ligand for alpha beta T cell receptor.

1990 • 39 citations

The role of thymic epithelium in the acquisition of tolerance

1990 • 37 citations

Characterization of stromal cell populations in the developing thymus of normal and nude mice

1984 • 35 citations

T cell receptor-mediated selection of functional rat CD8 T cells from defined immature thymocyte precursors in short-term suspension culture.

1991 • 30 citations

Newly generated thymocytes are not refractory to deletion when the α/β component of the T cell receptor is engaged by the superantigen staphylococcal enterotoxin B

1990 • 20 citations

T cell tolerance.

1990 • 15 citations

Characterization of Murine Thymic Stromal-Cell Lines Immortalized by Temperature-Sensitive Simian Virus 40 Large T or Adenovirus 5 E1a

1991 • 8 citations