Point mutations in the β chain CDR3 can alter the T cell receptor recognition pattern on an MHC class I\peptide complex over a broad interface area

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

Anatomy of the antibody molecule

1994 • 868 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

The Three-Dimensional Structure of Peptide-MHC Complexes

1995 • 817 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

Structural Basis of Plasticity in T Cell Receptor Recognition of a Self Peptide-MHC Antigen

1998 • 685 citations

SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat.

1988 • 638 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Somatic recombination in a murine T-cell receptor gene

1984 • 468 citations

Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.

1992 • 295 citations

Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.

1996 • 271 citations

Crystal Structure of the β Chain of a T Cell Antigen Receptor

1995 • 267 citations

Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes

1987 • 220 citations

Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α‐mRNA of BW5147 origin

1989 • 188 citations

Crystal Structure of the V _α Domain of a T Cell Antigen Receptor

1995 • 178 citations

The Specificity and Orientation of a TCR to its Peptide–MHC Class II Ligands

1996 • 177 citations

Atomic structure of an alpha beta T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody

1998 • 174 citations

Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.

1986 • 143 citations

Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor CαCδ region

1992 • 134 citations

How αβ T-cell receptors ‘see’ peptide/MHC complexes

1993 • 124 citations

T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.

1993 • 97 citations

Evidence that the antigen receptors of cytotoxic T lymphocytes interact with a common recognition pattern on the H-2Kb molecule

1995 • 89 citations

Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus.

1992 • 86 citations

Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase

1992 • 56 citations

Topology of T cell receptor-peptide/class I MHC interaction defined by charge reversal complementation and functional analysis

1997 • 41 citations

TCR recognition of the Hb(64-76)/I-Ek determinant: single conservative amino acid changes in the complementarity-determining region 3 dramatically alter antigen fine specificity.

1996 • 30 citations

Alloreactivity, Antigen Recognition and T-Cell Selection: Three Diverse T-Cell Recognition Problems with a Common Solution

1996 • 28 citations

An approach to the study of structure-function relationships of MHC class I molecules: isolation and serologic characterization of H-2Kb somatic cell variants.

1986 • 27 citations

Characterization of thymus-derived lymphocytes expressing Ti alpha-beta CD3 gamma delta epsilon zeta-zeta, Ti alpha-beta CD3 gamma delta epsilon eta-eta or Ti alpha-beta CD3 gamma delta epsilon zeta-zeta/zeta-eta antigen receptor isoforms: analysis by gene transfection.

1990 • 25 citations

Mapping the orientation of an antigenic peptide bound in the antigen binding groove of H-2Kb using a monoclonal antibody

1992 • 11 citations

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