The Three-Dimensional Structure of Peptide-MHC Complexes

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

Emerging Principles for the Recognition of Peptide Antigens by MHC Class I Molecules

1992 • 730 citations

STRUCTURE, FUNCTION, AND DIVERSITY OF CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULES

1990 • 693 citations

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 • 687 citations

The antigenic identity of peptide-MHC complexes: A comparison of the conformations of five viral peptides presented by HLA-A2

1993 • 681 citations

The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

1992 • 670 citations

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

1994 • 545 citations

A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2

1990 • 527 citations

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

1992 • 414 citations

Nature of polymorphism in HLA-A, -B, and -C molecules.

1988 • 379 citations

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

1987 • 367 citations

The three-dimensional structure of H-2Db at 2.4 Å resolution: Implications for antigen-determinant selection

1994 • 243 citations

Three-dimensional structure of a peptide extending from one end of a class I MHC binding site

1994 • 222 citations

Substitution at residue 227 of H–2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, cytotoxic T lymphocytes

1989 • 198 citations

Characteristics of endogenous peptides eluted from the class I MHC molecule HLA-B7 determined by mass spectrometry and computer modeling.

1993 • 164 citations

Peptides in positive and negative selection: A delicate balance

1994 • 153 citations

Evidence that multiple residues on both the α-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor

1988 • 151 citations

Allele-specific peptide ligand motifs of HLA-C molecules.

1993 • 128 citations

Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705.

1993 • 116 citations

A sequence pattern for peptides presented to cytotoxic T lymphocytes by HLA B8 revealed by analysis of epitopes and eluted peptides

1993 • 104 citations

The structure of the antigen-binding groove of major histocompatibility complex class I molecules determines specific selection of self-peptides.

1991 • 100 citations

Defining rules for the peptide-MHC class II interaction

1994 • 87 citations

Origin, structure and motifs of naturally processed MHC class II ligands

1994 • 84 citations

Molecular dynamics study of a complex between the human histocompatibility antigen HLA‐A2 and the IMP58‐66 nonapeptide from influenza virus matrix protein

1992 • 48 citations

Identification of T cell receptor recognition residues for a viral peptide presented by HLA B27

1994 • 43 citations

Pocket Mutations of HLA-B27 Show That Anchor Residues Act Cumulatively to Stabilize Peptide Binding

1994 • 39 citations

Five Viral Peptide-HLA-A2 Co-crystals

1994 • 32 citations

Peptide binding to the major histocompatibility complex molecules

1992 • 26 citations

Toward computational determination of peptide‐receptor structure

1993 • 25 citations

Molecular Modeling of the Class I Human Histocompatibility Molecule HLA‐A2 Presenting an Allele‐Specific Nonapeptide from Influenza Matrix Protein

1992 • 11 citations