Nitric Oxide Is a Physiological Substrate for Mammalian Peroxidases

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1992 • 2,725 citations

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

1986 • 2,416 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils

1998 • 1,494 citations

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

1994 • 1,274 citations

Peroxidases in chemistry and biology

1990 • 1,039 citations

[23] Oxidative chemistry of peroxynitrite

1994 • 981 citations

Studies on the chlorinating activity of myeloperoxidase.

1976 • 918 citations

Oxygen Metabolism and the Toxic Properties of Phagocytes

1980 • 886 citations

3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.

1997 • 840 citations

Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite

1997 • 778 citations

Simulation of the diffusion and reaction of endogenously produced nitric oxide.

1994 • 699 citations

Myeloperoxidase: a key regulator of neutrophil oxidant production

1997 • 641 citations

Myeloperoxidase-generated oxidants and atherosclerosis

2000 • 607 citations

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.

1994 • 596 citations

Chemical determination of free radical-induced damage to DNA

1991 • 523 citations

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice

1999 • 518 citations

Diffusion-limited Reaction of Free Nitric Oxide with Erythrocytes

1998 • 506 citations

Nitric oxide and iron proteins

1999 • 506 citations

Biological aspects of reactive nitrogen species

1999 • 486 citations

Stable markers of oxidant damage to proteins and their application in the study of human disease

1999 • 451 citations

Thiocyanate and chloride as competing substrates for myeloperoxidase

1997 • 392 citations

Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.

1996 • 375 citations

Inhibition of Cytochromes P450 by Nitric Oxide and a Nitric Oxide-Releasing Agent

1993 • 358 citations

Human Atherosclerotic Plaque Contains Both Oxidized Lipids and Relatively Large Amounts of α-Tocopherol and Ascorbate

1995 • 357 citations

Why nitric oxide?

1992 • 350 citations

X-ray crystal structure of canine myeloperoxidase at 3 Å resolution

1992 • 312 citations

Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria.

1996 • 310 citations

Severe Impairment in Early Host Defense againstCandida albicansin Mice Deficient in Myeloperoxidase

1999 • 304 citations

Structure and Function of Oxidation–Reduction Enzymes

1972 • 270 citations

Human neutrophils employ chlorine gas as an oxidant during phagocytosis.

1996 • 258 citations

Eosinophil Peroxidase Nitrates Protein Tyrosyl Residues

1999 • 257 citations

Nitric Oxide Inhibition of Lipid Peroxidation: Kinetics of Reaction with Lipid Peroxyl Radicals and Comparison with α-Tocopherol

1997 • 252 citations

Formation of Nitric Oxide–Derived Oxidants by Myeloperoxidase in Monocytes

1999 • 229 citations

Mechanism of Reaction of Myeloperoxidase with Nitrite

2000 • 221 citations

[52] Antimicrobial activity of myeloperoxidase

1984 • 208 citations

Neuronal Nitric Oxide Synthase Self-inactivates by Forming a Ferrous-Nitrosyl Complex during Aerobic Catalysis

1995 • 195 citations

Nitric Oxide Modulates the Catalytic Activity of Myeloperoxidase

2000 • 195 citations

Determination of nitrate and nitrite by high-pressure liquid chromatography: Comparison with other methods for nitrate determination

1980 • 190 citations

[13] Nitric oxide-cyclic GMP signal transduction system

1996 • 183 citations

The participation of nitric oxide in cell free- and its restriction of macrophage-mediated oxidation of low-density lipoprotein

1992 • 179 citations

Human eosinophil peroxidase: purification and characterization.

1985 • 174 citations

Human Neutrophils Employ the Myeloperoxidase-Hydrogen Peroxide-Chloride System to Oxidize α-Amino Acids to a Family of Reactive Aldehydes

1998 • 170 citations

Spectral and Kinetic Studies on the Formation of Myeloperoxidase Compounds I and II: Roles of Hydrogen Peroxide and Superoxide

1994 • 133 citations

Some properties of human eosinophil peroxidase, a comparison with other peroxidases

1984 • 124 citations

Stopped-Flow Analysis of CO and NO Binding to Inducible Nitric Oxide Synthase

1998 • 104 citations

p-Hydroxyphenylacetaldehyde Is the Major Product of L-Tyrosine Oxidation by Activated Human Phagocytes

1996 • 103 citations

Leukocytes Utilize Myeloperoxidase-Generated Nitrating Intermediates as Physiological Catalysts for the Generation of Biologically Active Oxidized Lipids and Sterols in Serum

1999 • 92 citations

Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system

1990 • 89 citations

15-Lipoxygenase Catalytically Consumes Nitric Oxide and Impairs Activation of Guanylate Cyclase

1999 • 88 citations

Human eosinophil peroxidase: a novel isolation procedure, spectral properties and chlorinating activity

1981 • 82 citations

p-Hydroxyphenylacetaldehyde, the Major Product of l-Tyrosine Oxidation by the Myeloperoxidase-H2O2-Chloride System of Phagocytes, Covalently Modifies ε-Amino Groups of Protein Lysine Residues

1997 • 81 citations

The Effect of Nitric Oxide Release Rates on the Oxidation of Human Low Density Lipoprotein

1997 • 78 citations

Action of nitric oxide as an antioxidant against oxidation of soybean phosphatidylcholine liposomal membranes

1995 • 78 citations

Kinetic studies on the reaction of compound II of myeloperoxidase with ascorbic acid. Role of ascorbic acid in myeloperoxidase function.

1990 • 76 citations

The chlorinating potential of the human monocyte

1983 • 71 citations

Purification of horse eosinophil peroxidase

1982 • 60 citations

Studies on Myeloperoxidase Activity. I. Spectrophotometry of the MPO-H2O2 Compound.

1963 • 54 citations

Reactions of nitric oxide and peroxynitrite with organic molecules and ferrihorseradish peroxidase: Interference with the determination of hydrogen peroxide

1996 • 53 citations

The reactions of copper proteins with nitric oxide

1999 • 52 citations

Resonance Raman studies of lactoperoxidase.

1986 • 50 citations

The Reaction Rates of NO with Horseradish Peroxidase Compounds I and II

1999 • 47 citations

Kinetic analysis of the recombination of nitric oxide with ferrihemoproteins by the flash photolysis method

1982 • 27 citations

Crystal structure of nitric oxide inhibited cytochrome c peroxidase

1988 • 26 citations

"Ottorino Rossi" Award 1997. The biology of nitric oxide.

1997 • 8 citations