Human neutrophils employ chlorine gas as an oxidant during phagocytosis.

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Role of oxidized low density lipoprotein in atherogenesis.

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Protein Oxidation and Aging

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Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

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Studies on the chlorinating activity of myeloperoxidase.

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Enthalpy of decomposition of hydrogen peroxide by catalase at 25° C (with molar extinction coefficients of H2O2 solutions in the UV)

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Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts*1

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Oxygen Metabolism and the Toxic Properties of Phagocytes

1980 • 886 citations

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

1987 • 823 citations

Chlorination of Taurine by Human Neutrophils

1982 • 794 citations

The neutrophil: Function and clinical disorders

1978 • 670 citations

The biochemical basis of the NADPH oxidase of phagocytes

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The neutrophil: Function and clinical disorders

1979 • 628 citations

A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent.

1989 • 594 citations

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

1996 • 587 citations

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

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Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

1990 • 478 citations

Oxygen-Dependent Microbial Killing by Phagocytes

1978 • 448 citations

Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidase.

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Tissue Destruction by Neutrophils

1989 • 389 citations

[40] Preparation and characterization of chloramines

1986 • 345 citations

Chlorination of Tyrosyl Residues in Peptides by Myeloperoxidase and Human Neutrophils

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Assessment of chlorination by human neutrophils

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Role of oxidized low density lipoprotein in atherogenesis

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Structure and Function of Oxidation–Reduction Enzymes

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Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid

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Leukocytic Oxygen Activation and Microbicidal Oxidative Toxin

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Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Converts Low Density Lipoprotein Cholesterol into a Family of Chlorinated Sterols

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Neutrophil Receptors for IgG and Complement: Their Roles in the Attachment and Ingestion Phases of Phagocytosis

1976 • 210 citations

Different Roles of IgG and Complement Receptors in Phagocytosis by Polymorphonuclear Leukocytes

1975 • 161 citations

Phagolysosomal pH of human neutrophils

1984 • 154 citations

Cholesterol Chlorohydrin Synthesis by the Myeloperoxidase-Hydrogen Peroxide-Chloride System: Potential Markers for Lipoproteins Oxidatively Damaged by Phagocytes

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Kinetic Studies on the Chloramines. I. The Rates of Formation of Monochloramine, N-Chlormethylamine and N-Chlordimethylamine

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Phagocytosing macrophages exclude proteins from the zones of contact with opsonized targets

1984 • 134 citations

Myeloperoxidase-catalyzed incorporation of amines into proteins: role of hypochlorous acid and dichloramines

1982 • 132 citations

p-Hydroxyphenylacetaldehyde Is the Major Product of L-Tyrosine Oxidation by Activated Human Phagocytes

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Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system

1990 • 89 citations

Crystallization and Properties of Myeloperoxidase from Normal Human Leukocytes

1986 • 61 citations

Neutrophil bactericidal activity against Staphylococcus aureus adherent on biological surfaces. Surface-bound extracellular matrix proteins activate intracellular killing by oxygen-dependent and -independent mechanisms.

1990 • 54 citations

The Role of Protected Extracellular Compartments in Interactions between Leukocytes, and Platelets, and Fibrin/Fibrinogen Matricesa

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Cellular mechanisms for the oxidative modification of lipoproteins

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Electrophilic Halogenation: Reaction Pathways Involving Attack by Electrophilic Halogens on Unsaturated Compounds

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[7] Methods for the study of receptor-mediated phagocytosis

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Oxygen tension within the arterial wall: Relationship to altered bioenergetic metabolism and lipid accumulation

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Myeloperoxidase deficiency

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[21] Hemolytic holes in human erythrocyte membrane ghosts

1989 • 18 citations