Participation of Survivin in mitotic and apoptotic activities of normal and tumor‐derived cells*

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

IAP family proteins---suppressors of apoptosis

1999 • 2,570 citations

Taxol stabilizes microtubules in mouse fibroblast cells.

1980 • 1,942 citations

Control of apoptosis and mitotic spindle checkpoint by survivin

1998 • 1,881 citations

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

1998 • 1,243 citations

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1995 • 1,237 citations

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1993 • 1,049 citations

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 • 1,027 citations

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1998 • 985 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1995 • 728 citations

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

1999 • 613 citations

A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases

1998 • 611 citations

Regulation of apoptosis at cell division by p34 ^cdc2 phosphorylation of survivin

2000 • 606 citations

Expression of survivin and its relationship to loss of apoptosis in breast carcinomas

2000 • 561 citations

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

2000 • 534 citations

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

1996 • 515 citations

Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.

1998 • 512 citations

A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy.

2000 • 491 citations

Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.

1998 • 473 citations

Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting

1998 • 413 citations

An exegesis of IAPs: salvation and surprises from BIR motifs

1999 • 345 citations

Survivin promotes cell proliferation in human hepatocellular carcinoma

2000 • 329 citations

The Drosophila caspase DRONC is regulated by DIAP1

2000 • 322 citations

Inhibition of melanoma tumor growth in vivo by survivin targeting

2001 • 290 citations

The Survivin-like C. elegans BIR-1 Protein Acts with the Aurora-like Kinase AIR-2 to Affect Chromosomes and the Spindle Midzone

2000 • 252 citations

Human Survivin Is a Kinetochore-Associated Passenger Protein

2000 • 235 citations

Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death

2000 • 233 citations

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis

1999 • 222 citations

Generation of survivin-specific CD8+ T effector cells by dendritic cells pulsed with protein or selected peptides.

2000 • 218 citations

Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

2000 • 205 citations

Survivin initiates cell cycle entry by the competitive interaction with Cdk4/p16INK4a and Cdk2/Cyclin E complex activation

2000 • 196 citations

Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

1999 • 194 citations

Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions

2000 • 174 citations

Expression of the apoptosis inhibitor, survivin, in nonmelanoma skin cancer and gene targeting in a keratinocyte cell line.

1999 • 167 citations

drICE is an essential caspase required for apoptotic activity in Drosophila cells

1997 • 143 citations

Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events

1999 • 120 citations

Mechanisms and control of programmed cell death in invertebrates

1998 • 119 citations

Deterin, a New Inhibitor of Apoptosis from Drosophila melanogaster

2000 • 96 citations

S. pombe Pbh1p: an inhibitor of apoptosis domain containing protein is essential for chromosome segregation

1999 • 31 citations

Transcriptional regulation of an unusual trypsin-related protein expressed during insect metamorphosis

1993 • 9 citations