Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

Real time quantitative PCR.

1996 • 6,155 citations

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Control of apoptosis and mitotic spindle checkpoint by survivin

1998 • 1,881 citations

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1997 • 1,316 citations

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

1998 • 1,243 citations

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1993 • 1,049 citations

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

1999 • 750 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1995 • 728 citations

Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer.

1998 • 720 citations

An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs

1994 • 530 citations

Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.

1998 • 512 citations

Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.

1998 • 473 citations

Immunohistochemical analysis of in vivo patterns of Bcl-X expression.

1994 • 429 citations

Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting

1998 • 413 citations

2′-O-(2-Methoxy)ethyl-modified Anti-intercellular Adhesion Molecule 1 (ICAM-1) Oligonucleotides Selectively Increase the ICAM-1 mRNA Level and Inhibit Formation of the ICAM-1 Translation Initiation Complex in Human Umbilical Vein Endothelial Cells

1997 • 366 citations

Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation

1999 • 251 citations

A Giant Ubiquitin-conjugating Enzyme Related to IAP Apoptosis Inhibitors

1998 • 248 citations

Characterization of a Potent and Specific Class of Antisense Oligonucleotide Inhibitor of Human Protein Kinase C-α Expression

1999 • 222 citations

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis

1999 • 222 citations

A Human IAP-Family Gene, Apollon, Expressed in Human Brain Cancer Cells

1999 • 217 citations

Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

1999 • 194 citations

Cytoskeletal organization following cannabinoid treatment in undifferentiated and differentiated PC12 cells

1992 • 64 citations