Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Apoptosis by Death Factor

1997 • 5,038 citations

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1995 • 1,237 citations

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 • 1,027 citations

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1995 • 976 citations

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control

1997 • 875 citations

An evolutionary perspective on apoptosis

1994 • 758 citations

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM

1988 • 631 citations

Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria

1994 • 577 citations

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

1996 • 515 citations

Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.

1998 • 512 citations

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

1997 • 502 citations

An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes

1989 • 305 citations

Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus

1997 • 254 citations

Two Mammalian Genes Transcribed from Opposite Strands of the Same DNA Locus

1987 • 195 citations

Effects of BCL-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells

1994 • 162 citations

BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense.

1990 • 157 citations

Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domain

1994 • 151 citations

The iap genes: unique arbitrators of cell death

1997 • 95 citations

An antisense RNA involved in p53 mRNA maturation in murine erythroleukemia cells induced to differentiate.

1989 • 93 citations

Tandem genes and clustered genes

1995 • 86 citations

Xa receptor EPR‐1

1995 • 86 citations

Effector Cell Protease Receptor-1 Is a Vascular Receptor for Coagulation Factor Xa

1996 • 79 citations

Antisense oligonucleotide inhibitors for the treatment of cancer: 2. Toxicological properties of phosphorothioate oligodeoxynucleotides.

1997 • 63 citations

Independent regulation of transcription of the two strands of the c-myc gene.

1987 • 63 citations

Naturally Occurring Antisense Transcripts Are Present in Chick Embryo Chondrocytes Simultaneously with the Down-regulation of the α1(I) Collagen Gene

1995 • 60 citations

Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene.

1992 • 43 citations