Regulation of COL1A1 expression in type I collagen producing tissues: Identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Current Protocols in Molecular Biology

2001 • 2,451 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

1994 • 1,271 citations

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

1989 • 679 citations

A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis

1993 • 677 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Construction of DNA sequences complementary to rat .alpha.1 and .alpha.2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D

1984 • 568 citations

Expression of differentiated function by mineralizing cultures of chicken osteoblasts

1987 • 397 citations

Effect of insulinlike growth factor I on DNA and protein synthesis in cultured rat calvaria.

1980 • 387 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape

1992 • 296 citations

MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer

1992 • 290 citations

The Msh-like homeobox genes define domains in the developing vertebrate eye

1991 • 217 citations

Purification of the human immunodeficiency virus type 1 enhancer and TAR binding proteins EBP-1 and UBP-1.

1988 • 201 citations

Modulation by recombinant interleukin 1 of synthesis of types I and III collagens and associated procollagen mRNA levels in cultured human cells.

1987 • 195 citations

Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins.

1993 • 182 citations

Constitutive and IL-6-induced nuclear factors that interact with the human C-reactive protein promoter.

1990 • 176 citations

Effects of Glucocorticoids on Fetal Rat Bone Collagen Synthesis in Vitro*

1979 • 175 citations

Functional analysis of human alpha 1(I) procollagen gene promoter. Differential activity in collagen-producing and -nonproducing cells and response to transforming growth factor beta 1.

1994 • 158 citations

Isolation and characterization of the rat α1(I) collagen promoter

1989 • 145 citations

Msx-2/Hox 8.1: a transcriptional regulator of the rat osteocalcin promoter.

1994 • 138 citations

Differential utilization of regulatory domains within the alpha 1(I) collagen promoter in osseous and fibroblastic cells.

1992 • 134 citations

Parathyroid hormone alters collagen synthesis and procollagen mRNA levels in fetal rat calvaria.

1980 • 127 citations

Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice

1994 • 104 citations

Hormonal Regulation of Collagen Synthesis in a Clonal Rat Osteosarcoma Cell Line*

1986 • 100 citations

Cloning and characterization of the rat bone sialoprotein gene promoter

1993 • 99 citations

Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent upon homeodomain and CP1 binding motifs.

1994 • 98 citations

Transcription factors AP-3 and AP-2 interact with the SV40 enhancer in a mutually exclusive manner.

1989 • 90 citations

Identification of a ras-Activated Enhancer in the Mouse Osteopontin Promoter and Its Interaction with a Putative ETS-Related Transcription Factor Whose Activity Correlates with the Metastatic Potential of the Cell

1995 • 84 citations

An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice.

1991 • 83 citations

The mRNAs for the pro-alpha 1(I) and pro-alpha 2(I) chains of type I procollagen are translated at the same rate in normal human fibroblasts and in fibroblasts from two variants of osteogenesis imperfecta with altered steady state ratios of the two mRNAs.

1983 • 79 citations

Cell-specific expression of alpha 1(I) collagen-hGH minigenes in transgenic mice.

1994 • 74 citations

Conservation of binding sites for regulatory factors in the coordinately expressed α1(I) and α2(I) collagen promoters

1991 • 71 citations

Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cells.

1993 • 64 citations

Nucleotides Flanking a Conserved TAAT Core Dictate the DNA Binding Specificity of Three Murine Homeodomain Proteins

1993 • 63 citations

Multiple regulatory effects by transforming growth factor-beta on type I collagen levels in osteoblast-enriched cultures from fetal rat bone.

1992 • 57 citations

Expression of a human homeobox-containing gene is regulated by 1,25(OH)2D3 in bone cells

1993 • 52 citations

Parathyroid hormone represses alpha 1(I) collagen promoter activity in cultured calvariae from neonatal transgenic mice.

1993 • 50 citations

Regulation of the alpha 1(I) collagen promoter in vascular smooth muscle cells. Comparison with other alpha 1(I) collagen-producing cells in transgenic animals and cultured cells.

1994 • 42 citations

Interleukin-1α and Phorbol Ester Inhibit Collagen Synthesis in Osteoblastic MC3T3-E1 Cells by a Transcriptional Mechanism

1990 • 39 citations

Genomic Organization and Chromosome Localization of the Murine Homeobox Gene Pmx

1994 • 38 citations

Tissue- and development-specific expression in transgenic mice of a type I procollagen (COL1A1) minigene construct with 2.3 kb of the promoter region and 2 kb of the 3'-flanking region. Specificity is independent of the putative regulatory sequences in the first intron

1993 • 35 citations

Regulation of type I collagen synthesis. Total proalpha1(I) and proalpha2(I) mRNAs are maintained in a 2: 1 ratio under varying rates of collagen synthesis

1985 • 34 citations