MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

1991 • 1,564 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Pax-6, a murine paired box gene, is expressed in the developing CNS

1991 • 1,226 citations

The structure and function of the homeodomain

1989 • 1,007 citations

Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.

1989 • 984 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

A homologous protein-coding sequence in drosophila homeotic genes and its conservation in other metazoans

1984 • 920 citations

A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

1989 • 919 citations

Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

1991 • 897 citations

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

1991 • 874 citations

A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

1989 • 863 citations

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

1989 • 861 citations

Plasticity of the Differentiated State

1985 • 839 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

Identification of MRF4: a new member of the muscle regulatory factor gene family.

1989 • 779 citations

MyoD family: a paradigm for development?

1990 • 776 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

1989 • 662 citations

A regulatory hierarchy for cell specialization in yeast

1989 • 612 citations

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes.

1989 • 605 citations

In situ detection of sequence-specific DNA binding activity specified by a recombinant bacteriophage.

1988 • 535 citations

The sequence specificity of homeodomain-DNA interaction

1988 • 501 citations

Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila

1986 • 497 citations

Human SRF-related proteins: DNA-binding properties and potential regulatory targets.

1991 • 446 citations

Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.

1986 • 432 citations

Pax: A murine multigene family of paired box-containing genes

1991 • 427 citations

A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

1989 • 399 citations

Homeobox proteins as sequence-specific transcription factors

1988 • 397 citations

The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system

1990 • 383 citations

Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

1989 • 373 citations

[38] Nucleic acid hybridization in cytological preparations

1971 • 368 citations

Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Sp1.

1990 • 334 citations

Transcripts of α-cardiac and α-skeletal actins are early markers for myogenesis in the mouse embryo

1988 • 330 citations

The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures.

1990 • 326 citations

Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene.

1989 • 326 citations

Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos

1989 • 316 citations

HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors.

1992 • 312 citations

A molecular analysis of mouse development from 8 to 10 dayspost coitumdetects changes only in embryonic globin expression

1987 • 298 citations

HNF-1, a member of a novel class of dimerizing homeodomain proteins.

1991 • 286 citations

Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization.

1990 • 278 citations

Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products.

1991 • 264 citations

Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene.

1988 • 248 citations

A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila

1990 • 237 citations

The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.

1988 • 236 citations

A new Drosophila homeo box gene is expressed in mesodermal precursor cells of distinct muscles during embryogenesis.

1990 • 216 citations

Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages.

1988 • 172 citations

Muscle-specific expression of the troponin I gene requires interactions between helix-loop-helix muscle regulatory factors and ubiquitous transcription factors.

1991 • 171 citations

Effect of cell history on response to helix–loop–helix family of myogenic regulators

1990 • 164 citations

Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis.

1991 • 159 citations

Identification of a Novel Proline-directed Serine/Threonine Protein Kinase in Rat Pheochromocytoma

1989 • 159 citations

Developmental regulation of creatine kinase gene expression by myogenic factors in embryonic mouse and chick skeletal muscle

1991 • 125 citations

The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription.

1992 • 110 citations

The Upstream Muscle-Specific Enhancer of the Rat Muscle Creatine Kinase Gene Is Composed of Multiple Elements

1989 • 109 citations

Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene.

1988 • 108 citations

The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme

1991 • 106 citations

Differential trans-activation of a muscle-specific enhancer by myogenic helix-loop-helix proteins is separable from DNA binding.

1991 • 89 citations

The gooseberry-zipper region of Drosophila : five genes encode different spatially restricted transcripts in the embryo

1987 • 87 citations

Homeobox genes in mouse development.

1991 • 83 citations

Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding.

1991 • 81 citations

The upstream muscle-specific enhancer of the rat muscle creatine kinase gene is composed of multiple elements.

1989 • 43 citations

Rabbit muscle creatine kinase: genomic cloning, sequencing, and analysis of upstream sequences important for expression in myocytes

1991 • 26 citations

Despite expression in embryonic visceral mesoderm, H2.0 is not essential for Drosophila visceral muscle morphogenesis

1991 • 20 citations