A Germinal Center‐like Reaction in the Nonlymphoid Tissue of the Synovial Membrane^a

Intraclonal generation of antibody mutants in germinal centres

1991 • 1,083 citations

Maturation of the immune response in germinal centers

1991 • 904 citations

The role of clonal selection and somatic mutation in autoimmunity

1987 • 714 citations

Analysis of somatic mutation in five B cell subsets of human tonsil.

1994 • 667 citations

Mutation Drift and Repertoire Shift in the Maturation of the Immune Response

1987 • 635 citations

Germinal centres in T-cell-dependent antibody responses

1992 • 442 citations

Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis.

1996 • 433 citations

Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells.

1991 • 278 citations

The maturation of the immune response

1993 • 219 citations

Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis

1984 • 179 citations

The Identification of Germinal Centres and Follicular Dendritic Cell Networks in Rheumatoid Synovial Tissue

1995 • 167 citations

Human organ-specific autoimmune disease. Molecular cloning and expression of an autoantibody gene repertoire for a major autoantigen reveals an antigenic immunodominant region and restricted immunoglobulin gene usage in the target organ.

1993 • 139 citations

DETECTION OF CLONALLY EXPANDED SALIVARY GLAND LYMPHOCYTES IN SJÖGREN'S SYNDROME

1989 • 75 citations

The nature of autoantigens targeted in autoimmune endocrine diseases

1996 • 69 citations

The Molecular Pathology of Autoimmune Diseases

1993 • 66 citations

Individual germinal centres of myasthenia gravis human thymuses contain polyclonal activated B cells that express all the VH and VK families

1991 • 36 citations

Isolation of germinal centerlike events from human spleen RNA. Somatic hypermutation of a clonally related VH6DJH rearrangement expressed with IgM, IgG, and IgA.

1993 • 23 citations