Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases.

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions.

1989 • 451 citations

Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.

1990 • 347 citations

Base pairing involving deoxyinosine: implications for probe design

1985 • 330 citations

Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents

1982 • 287 citations

Adaptation to alkylation resistance involves the induction of a DNA glycosylase

1982 • 283 citations

Hypoxanthine in deoxyribonucleic acid: generation by heat-induced hydrolysis of adenine residues and release in free form by a deoxyribonucleic acid glycosylase from calf thymus

1980 • 177 citations

Physical association of the 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites.

1989 • 159 citations

Two enzymes are required for strand incision in repair of alkylated DNA

1977 • 153 citations

Excision of 5'-terminal deoxyribose phosphate from damaged DNA is catalyzed by the Fpg protein of Escherichia coli.

1992 • 147 citations

3-Methyladenine residues in DNA induce the SOS function sfiA in Escherichia coli.

1984 • 136 citations

Purification and characterization of human 3-methyladenine-DNA glycosylase

1993 • 136 citations

Site-specific mutagenesis in vivo by single methylated or deaminated purine bases

1986 • 118 citations

Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene.

1989 • 105 citations

Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase.

1990 • 104 citations

Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine.

1992 • 102 citations

Human cDNA expressing a functional DNA glycosylase excising 3-methyladenine and 7-methylguanine

1991 • 102 citations

Studies on nucleic acid interactions I. Stabilities of mini-duplexes (dG₂A₄XA₄G₂.dC₂T₄YT₄C₂) and self-complementary d(GGGAAXYTTCCC) containing deoxyinosine and other mismatched bases

1986 • 100 citations

Enzymatic excision of free hypoxanthine from polydeoxynucleotides and DNA containing deoxyinosine monophosphate residues.

1978 • 99 citations

Structure and expression of the alkA gene of Escherichia coli involved in adaptive response to alkylating agents.

1984 • 98 citations

Cleavage and binding of a DNA fragment containing a single 8-oxoguanine by wild type and mutant FPG proteins

1993 • 91 citations

Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.

1990 • 84 citations

Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere.

1993 • 61 citations

Metabolism of dITP in HeLa cell extracts, incorporation into DNA by isolated nuclei and release of hypoxanthine from DNA by a hypoxanthine-DNA glycosylase activity

1982 • 47 citations

Preferential recognition of I·T base-pairs in the initiation of excision-repair by hypoxanthine-DNA glycosylase

1991 • 44 citations

Excision of the imidazole ring-opened form of N-2-aminofluorene-C(8)-guanine adduct in poly(dG-dC) by Escherichia coli fonnamidopyrimidine-DNA glycosylase

1989 • 42 citations

Release of N² ,3-ethanoguanine from haloethylnitrosourea-treated DNA by Escherichia coil 3-methyladenine DNA glycosylase II

1991 • 39 citations

Regulation of hypoxanthine DNA glycosylase in normal human and Bloom's syndrome fibroblasts.

1986 • 31 citations

Induction of mutation of a synthetic c-Ha-ras gene containing hypoxanthine.

1992 • 31 citations