Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli.

1977 • 513 citations

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

1980 • 438 citations

DNA N-glycosylases and UV repair

1980 • 307 citations

Adaptation to alkylation resistance involves the induction of a DNA glycosylase

1982 • 283 citations

Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA

1979 • 260 citations

Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichla coli

1979 • 257 citations

An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1977 • 225 citations

Properties of 3-methyladenine-DNA glycosylase from Escherichia coli

1978 • 190 citations

Repair of O6-methylguanine in adapted Escherichia coli.

1978 • 180 citations

Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea and ethyl methanesulphonate in relation to induction of thymic lymphoma. Some applications of high-pressure liquid chromatography

1978 • 177 citations

Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N′-nitro-N-nitrosoguanidine

1970 • 173 citations

Escherichia coli mutants deficient in 3-methyladenine-DNA glycosylase

1980 • 146 citations

Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines.

1981 • 121 citations

Enzymatic excision of free hypoxanthine from polydeoxynucleotides and DNA containing deoxyinosine monophosphate residues.

1978 • 99 citations

Methylated purines in the deoxyribonucleic acid of various Syrian-golden-hamster tissues after administration of a hepatocarcinogenic dose of dimethylnitrosamine

1976 • 98 citations

Isolation of mutants of Escherichia coli with increased resistance to alkylating agents: Mutants deficient in thiols and mutants constitutive for the adaptive response

1980 • 95 citations

Removal of minor methylation products 7-methyl adenine and 3-methylguanine from DNA ofescherichia coli treated with dimethyl sulphate

1976 • 84 citations

A DNA glycosylase from Escherichia coli that releases free urea from a polydeoxyribonucleotide containing fragments of base residues

1980 • 82 citations

Reaction of alkylating mutagens and carcinogens with nucleic acids: N-3 of guanine as a site of alkylation by N-methyl-N-nitrosourea and dimethyl sulphate

1972 • 63 citations

Efficiency of the adaptive response of Escherichia coli to alkylating agents

1980 • 61 citations

Release of 7-methylguanine residues from alkylated DNA by extracts of Micrococcus luteus and Escherichia coli.

1981 • 55 citations

The Excision of N‐Methyl‐N‐nitrosourea‐Induced Lesions from the DNA of Chinese Hamster Cells as Measured by the Loss of Sites Sensitive to an Enzyme Extract that Excises 3‐Methylpurines but not O⁶‐Methylguanine

1979 • 21 citations

Enhancement of deoxyribonucleic acid polymerase I-directed repair synthesis in toluene-treated Escherichia coli after growth in the presence of low levels of N-methyl-N'-nitro-N-nitrosoguanidine

1979 • 7 citations