Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine.

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1991 • 1,173 citations

DNA Repair Enzymes

1982 • 905 citations

Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction.

1982 • 398 citations

Enzymic oxidation of ethyl carbamate to vinyl carbamate and its role as an intermediate in the formation of 1,N6-ethenoadenosine

1991 • 153 citations

Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase

1991 • 142 citations

Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16.

1991 • 132 citations

Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines.

1981 • 121 citations

Interactions of vinyl chloride with rat-liver DNA in vivo

1978 • 110 citations

1,N⁶ formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate

1990 • 108 citations

Human cDNA expressing a functional DNA glycosylase excising 3-methyladenine and 7-methylguanine

1991 • 102 citations

1,N⁶-etheno-2′ -deoxyadenosine and 3,N⁴-etheno-2′-deoxycytidine detected by monoclonal antibodies in lung and liver DNA of rats exposed to vinyl chloride

1989 • 82 citations

Labeled 1,N⁶-ethenoadenosine and 3,N⁴-ethenocytidine in hepatic RNA of mice given [ethyl-1,2-³H or ethyl-1-¹⁴C] ethyl carbamate (urethan)

1982 • 61 citations

Partial purification and characterization of 3-methyladenine-DNA glycosylase from human placenta

1982 • 37 citations

Human cells contain protein specifically binding to a single 1,N6-ethenoadenine in a DNA fragment.

1991 • 36 citations

Further purification and characterization of human 3-methyladenine-DNA glycosylase Evidence for broad specificity

1984 • 27 citations

Partial purification of a human DNA glycosylase acting on the cyclic carcinogen adduct 1,N6-ethenodeoxyadenosine.

1992 • 25 citations

Purification and characterization of 3-methyladenine-DNA glycosylase from calf thymus.

1985 • 24 citations