Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

The Mosaic Genome of Warm-Blooded Vertebrates

1985 • 887 citations

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.

1987 • 802 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS

1988 • 645 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

1990 • 477 citations

A review of the molecular genetics of the human alpha-globin gene cluster

1989 • 443 citations

The highest gene concentrations in the human genome are in telomeric bands of metaphase chromosomes.

1992 • 342 citations

A major positive regulatory region located far upstream of the human alpha-globin gene locus.

1990 • 337 citations

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

1990 • 288 citations

The distribution of genes in the human genome

1991 • 255 citations

Ap endonucleases and dna glycosylases that recognize oxidative dna damage

1988 • 254 citations

Role of replication time in the control of tissue-specific gene expression.

1987 • 249 citations

Splicing of Messenger RNA Precursors

1987 • 219 citations

The William Allan memorial award address: X-chromosome inactivation and the location and expression of X-linked genes.

1988 • 180 citations

Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16

1991 • 165 citations

Cis-acting sequences regulating expression of the human α-globin cluster lie within constitutively open chromatin

1992 • 162 citations

Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.

1990 • 144 citations

Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase

1991 • 142 citations

Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16.

1991 • 132 citations

Clinical features and molecular analysis of the alpha thalassemia/mental retardation syndromes. I. Cases due to deletions involving chromosome band 16p13.3.

1990 • 129 citations

Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli.

1989 • 124 citations

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster

1990 • 112 citations

Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase.

1990 • 104 citations

Human cDNA expressing a functional DNA glycosylase excising 3-methyladenine and 7-methylguanine

1991 • 102 citations

Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.

1990 • 84 citations

Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents.

1992 • 46 citations

Age-dependent modulation of tissue-specific repair activity for 3-methyladenine and O6-methylguanine in DNA in inbred mice

1989 • 41 citations

Properties and Mechanism of Action of Eukaryotic 3-Methyladenine-DNA Glycosylases

1987 • 26 citations

Tissue-specific variation in repair activity for 3-methyladenine in DNA in two stocks of mice

1988 • 19 citations

Human ?-globin gene expression is silenced by terminal truncation of chromosome 16p beginning immediately 3? of the ?-globin gene

1992 • 19 citations