Endocytosis of the Viral Chemokine Receptor US28 Does Not Require Beta‐Arrestins But Is Dependent on the Clathrin‐Mediated Pathway

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling.

2001 • 1,794 citations

International union of pharmacology. XXII. Nomenclature for chemokine receptors.

2000 • 1,771 citations

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

Altered Trafficking of Lysosomal Proteins in Hermansky-Pudlak Syndrome Due to Mutations in the β3A Subunit of the AP-3 Adaptor

1999 • 663 citations

Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles

2001 • 626 citations

The β ₂ -adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

1999 • 615 citations

Molecular Architecture and Functional Model of the Endocytic AP2 Complex

2002 • 601 citations

Dynamin and β-Arrestin Reveal Distinct Mechanisms for G Protein-coupled Receptor Internalization

1996 • 450 citations

Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors

2001 • 446 citations

Clathrin and adaptors

1998 • 383 citations

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

1997 • 382 citations

Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane.

1988 • 356 citations

beta -Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking

2001 • 346 citations

Viral exploitation and subversion of the immune system through chemokine mimicry

2001 • 334 citations

Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin.

1994 • 333 citations

Dynamic Targeting of the Agonist-stimulated m2 Muscarinic Acetylcholine Receptor to Caveolae in Cardiac Myocytes

1997 • 275 citations

Trafficking of the HIV Coreceptor CXCR4

1999 • 258 citations

Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor

1997 • 252 citations

Constitutive Signaling of the Human Cytomegalovirus-encoded Chemokine Receptor US28

2001 • 239 citations

β-Arrestins Regulate Protease-activated Receptor-1 Desensitization but Not Internalization or Down-regulation

2002 • 223 citations

β-Arrestin Differentially Regulates the Chemokine Receptor CXCR4-mediated Signaling and Receptor Internalization, and This Implicates Multiple Interaction Sites between β-Arrestin and CXCR4

2000 • 214 citations

Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding.

1990 • 214 citations

Transferrin receptor and its recycling in HeLa cells.

1982 • 206 citations

Selective recognition of the membrane‐bound CX₃C chemokine, fractalkine, by the human cytomegalovirus‐encoded broad‐spectrum receptor US28

1998 • 203 citations

Endocytosis and Recycling of the HIV Coreceptor Ccr5

2000 • 185 citations

The Human Cytomegalovirus US28 Protein Is Located in Endocytic Vesicles and Undergoes Constitutive Endocytosis and Recycling

2001 • 178 citations

Internalization of the m2 Muscarinic Acetylcholine Receptor

1997 • 170 citations

Murine Cytomegalovirus (CMV) M33 and Human CMV US28 Receptors Exhibit Similar Constitutive Signaling Activities

2002 • 166 citations

Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2

1998 • 160 citations

Characterization of Sequence Determinants within the Carboxyl-terminal Domain of Chemokine Receptor CCR5 That Regulate Signaling and Receptor Internalization

2001 • 160 citations

Genetic analyses of adaptin function from yeast to mammals

2002 • 158 citations

β-Arrestins Regulate Interleukin-8-induced CXCR1 Internalization

1999 • 129 citations

Identification of a Motif in the Carboxyl Terminus of CXCR2 That Is Involved in Adaptin 2 Binding and Receptor Internalization

2000 • 113 citations

Protease-activated Receptor-1 Down-regulation

2000 • 81 citations

Chemokine receptor trafficking and viral replication

1999 • 70 citations

Characterization of RANTES- and aminooxypentane-RANTES-triggered desensitization signals reveals differences in recruitment of the G protein-coupled receptor complex.

1999 • 57 citations

Characterization of RANTES- and Aminooxypentane-RANTES- Triggered Desensitization Signals Reveals Differences in Recruitment of the G Protein-Coupled Receptor Complex

1999 • 48 citations