Altered Trafficking of Lysosomal Proteins in Hermansky-Pudlak Syndrome Due to Mutations in the β3A Subunit of the AP-3 Adaptor

The Biogenesis of Lysosomes

1989 • 1,583 citations

Degradation of CFTR by the ubiquitin-proteasome pathway

1995 • 1,285 citations

Protein Sorting by Transport Vesicles

1996 • 1,168 citations

Coat Proteins and Vesicle Budding

1996 • 955 citations

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

1995 • 885 citations

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1991 • 663 citations

UBIQUITIN AND THE CONTROL OF PROTEIN FATE IN THE SECRETORY AND ENDOCYTIC PATHWAYS

1998 • 617 citations

Albinism Associated with Hemorrhagic Diathesis and Unusual Pigmented Reticular Cells in the Bone Marrow: Report of Two Cases with Histochemical Studies

1959 • 539 citations

The AP-3 Adaptor Complex Is Essential for Cargo-Selective Transport to the Yeast Vacuole

1997 • 430 citations

Linking cargo to vesicle formation: receptor tail interactions with coat proteins

1997 • 408 citations

Mutation in AP-3 δ in the mocha Mouse Links Endosomal Transport to Storage Deficiency in Platelets, Melanosomes, and Synaptic Vesicles

1998 • 393 citations

AP-3: an adaptor-like protein complex with ubiquitous expression

1997 • 389 citations

Association of the AP-3 Adaptor Complex with Clathrin

1998 • 384 citations

The J. D. mutation in familial hypercholesterolemia: Amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors

1986 • 372 citations

Characterization of the Adaptor-related Protein Complex, AP-3

1997 • 369 citations

Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores

1997 • 329 citations

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3

1998 • 298 citations

Structural Determinants of Interaction of Tyrosine-based Sorting Signals with the Adaptor Medium Chains

1996 • 294 citations

A Function for the AP3 Coat Complex in Synaptic Vesicle Formation from Endosomes

1998 • 286 citations

Positional cloning of a gene for Hermansky–Pudlak syndrome, a disorder of cytoplasmic organelles

1996 • 281 citations

Intracellular trafficking of lysosomal membrane proteins

1996 • 277 citations

Melanosomes Are Specialized Members of the Lysosomal Lineage of Organelles

1995 • 270 citations

The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane.

1996 • 258 citations

The Medium Subunits of Adaptor Complexes Recognize Distinct but Overlapping Sets of Tyrosine-based Sorting Signals

1998 • 253 citations

Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

1992 • 252 citations

A novel adaptor-related protein complex.

1996 • 241 citations

The AP-3 complex: a coat of many colours

1998 • 237 citations

The Yeast Adaptor Protein Complex, AP-3, Is Essential for the Efficient Delivery of Alkaline Phosphatase by the Alternate Pathway to the Vacuole

1997 • 218 citations

ADP-Ribosylation Factor 1 (ARF1) Regulates Recruitment of the AP-3 Adaptor Complex to Membranes

1998 • 215 citations

A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.

1995 • 198 citations

Intracellular sorting and targeting of melanosomal membrane proteins: identification of signals for sorting of the human brown locus protein, gp75.

1995 • 159 citations

Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet

1997 • 154 citations

β-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein

1995 • 150 citations

Acidic Di-leucine Motif Essential for AP-3–dependent Sorting and Restriction of the Functional Specificity of the Vam3p Vacuolar t-SNARE

1998 • 143 citations

β3A-adaptin, a Subunit of the Adaptor-like Complex AP-3

1997 • 134 citations

A dileucine-like sorting signal directs transport into an AP-3-dependent, clathrin-independent pathway to the yeast vacuole

1998 • 112 citations

Functional Domain Mapping of the Clathrin-associated Adaptor Medium Chains ॖ1 and ॖ2

1997 • 93 citations

Two rat homologs of clathrin-associated adaptor proteins

1994 • 77 citations

Evidence for Locus Heterogeneity in Puerto Ricans with Hermansky-Pudlak Syndrome

1997 • 65 citations

Vesiculation and sorting from PC12-derived endosomes in vitro

1998 • 54 citations

The Lysosomal Granule Membrane Protein, Lamp-2, Is also Present in Platelet Dense Granule Membranes

1996 • 50 citations

Membrane protein biosynthesis — all sewn up?

1997 • 35 citations

Internalization and recycling to serotonin-containing granules of the 80K intégral membrane protein exposed on the surface of secreting rat basophilie leukaemia cells

1989 • 34 citations

Isolation of 115 human chromosome 8-specific expressed-sequence tags by Exon amplification

1995 • 16 citations

Cloning, expression pattern and mapping to 12p13.2→p13.1 of CLAPS3, a gene encoding a novel clathrin-adaptor small chain

1996 • 11 citations