Genetic Evidence Supporting Selection of the Vα14i NKT Cell Lineage from Double-Positive Thymocyte Precursors

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

1997 • 2,370 citations

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

1997 • 2,205 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

1996 • 1,885 citations

Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

2000 • 1,578 citations

IL-15 Receptor Maintains Lymphoid Homeostasis by Supporting Lymphocyte Homing and Proliferation

1998 • 1,293 citations

Lysosomal Glycosphingolipid Recognition by NKT Cells

2004 • 946 citations

An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells

2003 • 917 citations

The unconventional lifestyle of NKT cells

2002 • 756 citations

Requirement for RORγ in Thymocyte Survival and Lymphoid Organ Development

2000 • 714 citations

Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

2002 • 712 citations

T-bet Regulates the Terminal Maturation and Homeostasis of NK and Vα14i NKT Cells

2004 • 689 citations

A Thymic Precursor to the NK T Cell Lineage

2002 • 517 citations

Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes.

1995 • 517 citations

Thymic Origin of Intestinal αß T Cells Revealed by Fate Mapping of RORγt ⁺ Cells

2004 • 482 citations

NKT cells derive from double-positive thymocytes that are positively selected by CD1d

2001 • 421 citations

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

1994 • 418 citations

Overexpression of Natural Killer T Cells Protects Vα14-Jα281 Transgenic Nonobese Diabetic Mice against Diabetes

1998 • 390 citations

Editing of CD1d-Bound Lipid Antigens by Endosomal Lipid Transfer Proteins

2003 • 310 citations

Retinoid-related orphan receptor γ (RORγ) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis

2000 • 308 citations

Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis

1999 • 306 citations

Homeostasis of Vα14i NKT cells

2002 • 291 citations

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain

2001 • 288 citations

Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

1996 • 268 citations

Bcl-x and Bax Regulate Mouse Primordial Germ Cell Survival and Apoptosis during Embryogenesis

2000 • 245 citations

Differential dependence of CD4 ⁺ CD25 ⁺ regulatory and natural killer-like T cells on signals leading to NF-κB activation

2004 • 228 citations

Regulation of the TCRα repertoire by the survival window of CD4+CD8+ thymocytes

2002 • 227 citations

NK1.1+ T Cells in the Liver Arise in the Thymus and Are Selected by Interactions with Class I Molecules on CD4+CD8+ Cells

2000 • 217 citations

Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells

2004 • 202 citations

Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides

2002 • 201 citations

The ETS Protein MEF Plays a Critical Role in Perforin Gene Expression and the Development of Natural Killer and NK-T Cells

2002 • 191 citations

Thymic selection revisited: how essential is it?

2003 • 186 citations

Cutting Edge: NKT Cell Development Is Selectively Impaired in Fyn- Deficient Mice

1999 • 167 citations

Self-reactivity in thymic double-positive cells commits cells to a CD8αα lineage with characteristics of innate immune cells

2004 • 159 citations

Differential Requirement for Rel/Nuclear Factor κB Family Members in Natural Killer T Cell Development

2003 • 158 citations

Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice

2001 • 152 citations

Requirement for membrane lymphotoxin in natural killer cell development

1999 • 137 citations

Extrathymic development of V alpha 14-positive T cells.

1993 • 132 citations

Commitment toward the natural T (iNKT) cell lineage occurs at the CD4⁺8⁺stage of thymic ontogeny

2005 • 115 citations

Development and selection of NKT cells

2002 • 100 citations

NF-κB Controls Cell Fate Specification, Survival, and Molecular Differentiation of Immunoregulatory Natural T Lymphocytes

2004 • 100 citations

Cutting Edge: The Ets1 Transcription Factor Is Required for the Development of NK T Cells in Mice

2000 • 93 citations

The CD8 isoform CD8αα is not a functional homologue of the TCR co-receptor CD8αβ

2004 • 84 citations

Cutting Edge: The Ontogeny and Function of Va14Ja18 Natural T Lymphocytes Require Signal Processing by Protein Kinase Cθ and NF-κB

2004 • 76 citations

Thymic dependence of invariant Vα14+ Natural Killer-T cell development

1999 • 69 citations

Lack of directed Vα14‐Jα281 rearrangements in NK1⁺ T cells

1997 • 67 citations

Membrane Lymphotoxin Is Required for the Development of Different Subpopulations of NK T Cells

2000 • 67 citations

Induction of differentiation of pre-NKT cells to mature Vα14 NKT cells by granulocyte/macrophage colony-stimulating factor

1999 • 56 citations

Development of CD1d‐restricted NKT cells in the mouse thymus

2004 • 44 citations

Defective development of NK1.1+ T-cell antigen receptor αβ+ cells in zeta-associated protein 70 null mice with an accumulation of NK1.1+CD3− NK-like cells in the thymus

2001 • 40 citations

Selection of phenotypically distinct NK1.1+ T cells upon antigen expression in the thymus or in the liver

1999 • 32 citations

Contribution of double-negative thymic precursors to CD8α α+ intraepithelial lymphocytes of the gut in mice bearing TCR transgenes

2001 • 30 citations

Ontogeny of thymic NK1.1+ cells.

1997 • 13 citations