Cellular and Molecular Analysis of Mutagenesis Induced by Charged Particles of Defined Linear Energy Transfer

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

1991 • 944 citations

The Initial Physical Damage Produced by Ionizing Radiations

1989 • 255 citations

Isolation and characterization of the human apolipoprotein A-I gene.

1983 • 243 citations

The nature of mutants induced by ionising radiation in cultured hamster cells III. Molecular characterization of HPRT-deficient mutants induced by γ-rays or α-particles showing that the majority have deletions of all or part of the hprt gene

1986 • 207 citations

Nucleotide sequence of the human parathyroid hormone gene.

1983 • 206 citations

Measurement of mutagenesis in mammalian cells.

1979 • 136 citations

A fine-structure deletion map of human chromosome 11p: Analysis of J1 series hybrids

1989 • 126 citations

Chrysotile fiber is a strong mutagen in mammalian cells.

1992 • 122 citations

Genetics of Somatic Mammalian Cells: Lethal Antigens as Genetic Markers for Study of Human Linkage Groups

1971 • 121 citations

Measurement of low levels of x-ray mutagenesis in relation to human disease.

1986 • 110 citations

A comparison of mutation induction at the tk and hprt loci in human lymphoblastoid cells; quantitative differences are due to an additional class of mutations at the autosomal tk locus

1989 • 96 citations

The Chinese hamster HPRT gene: Restriction map, sequence analysis, and multiplex PCR deletion screen

1991 • 89 citations

Failla Memorial Lecture. Changing views of cellular radiosensitivity.

1994 • 79 citations

Oncogenic transfonnation by charged particles of defined LET

1988 • 79 citations

Charged-Particle Mutagenesis: I. Cytotoxic and Mutagenic Effects of High-LET Charged Iron Particles on Human Skin Fibroblasts

1992 • 78 citations

Molecular characterization of X-ray-induced mutations at the HPRT locus in plateau-phase Chinese hamster ovary cells

1990 • 66 citations

Molecular characterization of thymidine kinase mutants of human cells induced by densely ionizing radiation

1989 • 52 citations

Mapping large spontaneous deletion endpoints in the human HPRT gene

1988 • 52 citations

Molecular characterization of hprt mutants induced by low- and hgh-LET radiations in human cells

1990 • 48 citations

Southern Blot and Polymerase Chain Reaction Exon Analyses of HPRT - Mutations Induced by Radon and Radon Progeny

1994 • 47 citations

Molecular basis of X-ray-induced mutation at the HPRT locus in human lumphocytes

1986 • 47 citations

Mutation Induction and Relative Biological Effectiveness of Neutrons in Mammalian Cells: Experimental Observations

1988 • 44 citations

Mutation induction by charged particles of defined linear energy transfer

1988 • 43 citations

Analysis of large deletions in theHPRT gene of primary human fibroblasts using the polymerase chain reaction

1993 • 41 citations

The Prevalence of Multilocus Lesions in Radiation-Induced Mutants

1994 • 40 citations

Rapid screening for deletion mutations in the hprt gene using the polymerase chain reaction: X-ray and α-particle mutant spectra

1992 • 39 citations

Mutant Quantity and Quality in Mammalian Cells (A L ) Exposed to Cesium-137 Gamma Radiation: Effect of Caffeine

1995 • 39 citations

Megabase pair deletions in mutant mammalian cells following exposure to amsacrine, an inhibitor of DNA topoisomerase II.

1994 • 35 citations

The Effect of Dose Rate on X-Radiation-Induced Mutant Frequency and the Nature of DNA Lesions in Mouse Lymphoma L5178Y Cells

1990 • 35 citations

Genetic and biochemical analysis of the a1 cell-surface antigen associated with human chromosome 11.

1979 • 27 citations

Detection of deletion mutations extending beyond the HPRT gene by multiplex PCR analysis

1994 • 24 citations

Analysis of human chromosome 11 by somatic cell genetics: Reexamination of derivatives of human-hamster cell line J1

1987 • 19 citations

Molecular structural analysis of 417 HPRT mutations induced by restriction endonucleases in Chinese hamster ovary (CHO) cells

1995 • 18 citations

Molecular analysis of mutagenesis by high let radiation

1994 • 17 citations

Multiplex PCR analysis of in vivo‐arising deletion mutations in the hprt gene of human T‐lymphocytes

1994 • 16 citations

Cellular and Molecular Effects of Radon and Other Alpha Particle Emitters

1991 • 16 citations

Cytotoxic and Mutagenic Effects of Radon and Radon Daughters on Murine L5178Y Lines Differing in DNA Repair

1993 • 14 citations