Molecular characterization of thymidine kinase mutants of human cells induced by densely ionizing radiation

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Artificial transmutation of the gene

1996 • 966 citations

Genetic studies of the lac repressor

1977 • 610 citations

The Chemical Effects ofNucleic Acid Alkylation and Their Relation to Mutagenesis and Carcinogen esis

1975 • 446 citations

High-LET radiations induce a large proportion of non-rejoining DNA breaks

1977 • 360 citations

Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells

1983 • 293 citations

Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates

1981 • 262 citations

DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

1979 • 247 citations

Mutation assay at the thymidine kinase locus in diploid human lymphoblasts

1982 • 245 citations

Effect of gamma rays at the dihydrofolate reductase locus: Deletions and inversions

1986 • 233 citations

The nature of mutants induced by ionising radiation in cultured hamster cells III. Molecular characterization of HPRT-deficient mutants induced by γ-rays or α-particles showing that the majority have deletions of all or part of the hprt gene

1986 • 207 citations

Human thymidine kinase gene: molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells.

1984 • 205 citations

Repair of O6-methylguanine in adapted Escherichia coli.

1978 • 180 citations

Mutagenic specificity: Reversion of iso-1-cytochrome c mutants of yeast

1973 • 157 citations

Somatic mutations at a heterozygous autosomal locus in human cells occur more frequently by allele loss than by intragenic structural alterations

1986 • 150 citations

Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

1978 • 126 citations

Organization of the HPRT gene and related sequences in the human genome

1984 • 109 citations

Mutations induced by X-rays at the HPRT locus in cultured Chinese hamster cells are mostly large deletions

1985 • 100 citations

Use of HLA loss mutants to analyse the structure of the human major histocompatibility complex

1982 • 85 citations

γ-ray induced mutational spectrum in the lacI gene of escherichia coli

1980 • 82 citations

Quantitative and Molecular Analyses of Radiation-Induced Mutation in AS52 Cells

1986 • 82 citations

SOUTHERN ANALYSIS OF GENOMIC ALTERATIONS IN GAMMA-RAY-INDUCED APRT- HAMSTER CELL MUTANTS

1986 • 77 citations

Structure and sequence of mutations induced by ionizing radiation at selectable loci in Chinese hamster ovary cells

1986 • 70 citations

Toxicity and mutagenicity of X-rays and [125I]dUrd or [3H]TdR incorporated in the DNA of human lymphoblast cells

1983 • 64 citations

Molecular and biochemical analyses of spontaneous and X-ray induced mutants in human lymphoblastoid cells

1987 • 63 citations

Induction and Repair of DNA Strand Breaks in Cultured Mammalian Cells Following Fast Neutron Irradiation

1979 • 60 citations

Radiation-induced base substitution mutagenesis in single-stranded DNA phage M13

1981 • 57 citations

Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system.

1986 • 52 citations

Mapping of class I DNA sequences within the human major histocompatibility complex

1983 • 50 citations

Molecular Analysis of X-ray-induced Mutants at the HPRT Locus in V79 Chinese Hamster Cells

1986 • 49 citations

Molecular basis of X-ray-induced mutation at the HPRT locus in human lumphocytes

1986 • 47 citations

Locus Specificity for Mutation Induction in Human Cells Exposed to Accelerated Heavy Ions

1989 • 45 citations

Human Thymidine Kinase Gene: Molecular Cloning and Nucleotide Sequence of a cDNA Expressible in Mammalian Cells

1984 • 45 citations

Direct demonstration of genetic alterations at the dihydrofolate reductase locus after gamma irradiation.

1982 • 44 citations

Alterations of Gene Structure in Ethyl Methane Sulfonate-Induced Mutants of Mammalian Cells

1982 • 41 citations

DNA base sequence changes induced by ethyl methanesulfonate in a chromosomally integrated shuttle vector gene in mouse cells

1987 • 37 citations

Induction and Subsequent Repair of DNA Damage by Fast Neutrons in Cultured Mammalian Cells

1987 • 36 citations

Localization of the oncogene c‐erbA1 immediately proximal to the acute promyelocytic leukaemia breakpoint on chromosome 17

1985 • 36 citations

Molecular Characterization of¹²⁵I Decay and X-ray-induced HPRT Mutants in CHO Cells

1987 • 36 citations

GAMMA-RAY MUTAGENESIS IN BACTERIOPHAGE T4

1976 • 32 citations

Molecular specificity of X-radiation and its repair in Saccharomyces cerevisiae

1977 • 21 citations

Regional Localization of the Human Genes for Thymidine Kinase, Lactate Dehydrogenase-A, and Esterase-A<sub>4</sub>

1974 • 20 citations

High resolution chromosome analysis of constitutional and acquired t(15;17) maps c-erbA to Subband 17q11.2

1986 • 19 citations

Average and effective energies, fluencedose conversion factors and quality factors of the neutron spectra of some (alpha, n) sources.

1967 • 13 citations

Germ-line chromosomal localization of humanc-erb-A oncogene

1985 • 12 citations

Mutational alterations induced in yeast by ionizing radiation

1986 • 11 citations