Molecular structural analysis of 417 HPRT mutations induced by restriction endonucleases in Chinese hamster ovary (CHO) cells

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Enzymatic Restriction of Mammalian Cell DNA Using Pvu II and Bam H1: Evidence for the Double-strand Break Origin of Chromosomal Aberrations

1984 • 313 citations

Molecular mechanisms involved in the production of chromosomal aberrations

1984 • 303 citations

Mutation and inactivation of mammalian cells by various ionising radiations

1977 • 160 citations

Ionizing radiation-induced mutagenesis

1988 • 158 citations

Enzymatic Restriction of Mammalian Cell DNA: Evidence for Double-strand Breaks as Potentially Lethal Lesions

1985 • 146 citations

Cell electroporation is a highly efficient method for introducing restriction endonucleases into cells

1989 • 118 citations

Use of Restriction Endonucleases to Study Relationships between DNA Double-strand Breaks, Chromosomal Aberrations and Other End-points in Mammalian Cells

1988 • 112 citations

The Chinese hamster HPRT gene: Restriction map, sequence analysis, and multiplex PCR deletion screen

1991 • 89 citations

The Mutagenicity of α Particles from Plutonium-238

1982 • 68 citations

Molecular characterization of X-ray-induced mutations at the HPRT locus in plateau-phase Chinese hamster ovary cells

1990 • 66 citations

Mapping large spontaneous deletion endpoints in the human HPRT gene

1988 • 52 citations

Molecular characterization of hprt mutants induced by low- and hgh-LET radiations in human cells

1990 • 48 citations

Southern Blot and Polymerase Chain Reaction Exon Analyses of HPRT - Mutations Induced by Radon and Radon Progeny

1994 • 47 citations

The Crucial Role of DNA Double-Strand Breaks in Cellular Radiobiological Effects

1978 • 43 citations

Mutation induction by charged particles of defined linear energy transfer

1988 • 43 citations

The Genotoxicity of Alpha Particles in Human Embryonic Skin Fibroblasts

1984 • 41 citations

Rapid screening for deletion mutations in the hprt gene using the polymerase chain reaction: X-ray and α-particle mutant spectra

1992 • 39 citations

Neoplastic cell transformation by high-LET radiation: Molecular mechanisms

1989 • 32 citations

The restriction endonuclease Alu I induces chromosomal aberrations and mutations in the hypoxanthine phosphoribosyltransferase locus, but not in the Na+/K+ ATPase locus in V79 hamster cells

1986 • 29 citations

Restriction endonuclease Bam H I induces chromosomal aberrations in Chinese hamster ovary (CHO) cells

1986 • 28 citations

Biophysical Aspects of Auger Processes

1992 • 26 citations

The effectiveness of restriction endonucleases in cell killing and mutation

1993 • 23 citations

A mutation in codon 717 of the CHO-K1 elongation factor 2 gene prevents the first step in the biosynthesis of diphthamide

1992 • 20 citations

Deletion screening at the hypoxanthine‐guanine phosphoribosyltransferase locus in chinese hamster cells using the polymerase chain reaction

1989 • 20 citations

Induction of Chromosome Damage by Restriction Enzymes during Mitosis

1991 • 13 citations

Mutagenic effects of restriction enzymes in Chinese hamster cells: evidence for high mutagenicity of Sau3AI at the hprt locus

1993 • 11 citations

COMPARISON OF MUTATION INDUCTION BY EXTERNAL AND INTERNAL RADIATION SOURCES IN SYNCHRONIZED CHINESE HAMSTER OVARY (CHO) CELLS

1991 • 5 citations

Cytotoxicity of restriction enzyme-induced dna strand breaks in radiosensitive and radioresistant human tumor cell lines

1993 • 5 citations

Oblique propagation studies

1990 • 2 citations