Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

2003 • 1,790 citations

Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor

2007 • 1,712 citations

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

2000 • 1,596 citations

Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

2007 • 1,375 citations

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

2005 • 1,167 citations

Blimp-1 Orchestrates Plasma Cell Differentiation by Extinguishing the Mature B Cell Gene Expression Program

2002 • 1,000 citations

Blimp1 is a critical determinant of the germ cell lineage in mice

2005 • 999 citations

Molecular and Functional Profiling of Memory CD8 T Cell Differentiation

2002 • 962 citations

BCL-6 Represses Genes that Function in Lymphocyte Differentiation, Inflammation, and Cell Cycle Control

2000 • 862 citations

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells

2007 • 854 citations

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

2003 • 797 citations

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1994 • 752 citations

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

2008 • 616 citations

Heterogeneity and Cell-Fate Decisions in Effector and Memory CD8+ T Cell Differentiation during Viral Infection

2007 • 567 citations

Progressive differentiation and selection of the fittest in the immune response

2002 • 503 citations

CD8⁺ T‐cell memory in tumor immunology and immunotherapy

2006 • 472 citations

Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8 ⁺ memory T cell subsets

2004 • 466 citations

Regulation of Antigen-Specific CD8 ⁺ T Cell Homeostasis by Perforin and Interferon-γ

2000 • 452 citations

Repression of c- myc Transcription by Blimp-1, an Inducer of Terminal B Cell Differentiation

1997 • 412 citations

Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland

2006 • 410 citations

Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination

2005 • 382 citations

Anomalous Type 17 Response to Viral Infection by CD8 ⁺ T Cells Lacking T-bet and Eomesodermin

2008 • 381 citations

Regulation and Functions of Blimp-1 in T and B Lymphocytes

2008 • 361 citations

Transcriptional repressor Blimp-1 regulates T cell homeostasis and function

2006 • 361 citations

Cutting Edge: IL-12 Inversely Regulates T-bet and Eomesodermin Expression during Pathogen-Induced CD8+ T Cell Differentiation

2006 • 323 citations

CD8+ T cell contraction is controlled by early inflammation

2004 • 322 citations

Activation phenotype, rather than central– or effector–memory phenotype, predicts the recall efficacy of memory CD8+ T cells

2007 • 312 citations

Modelling T-cell memory by genetic marking of memory T cells in vivo

1999 • 310 citations

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

2006 • 305 citations

Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells

2008 • 286 citations

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells

2007 • 273 citations

Functional Properties and Lineage Relationship of CD8+ T Cell Subsets Identified by Expression of IL-7 Receptor α and CD62L

2005 • 273 citations

Arrested Differentiation, the Self-Renewing Memory Lymphocyte, and Vaccination

2001 • 264 citations

Memory B Cells without Somatic Hypermutation Are Generated from Bcl6-Deficient B Cells

2002 • 244 citations

Transcriptional regulator Id2 mediates CD8+ T cell immunity

2006 • 242 citations

Viral Infections Induce Abundant Numbers of Senescent CD8 T Cells

2001 • 236 citations

Generation of CD8 T Cell Memory Is Regulated by IL-12

2007 • 219 citations

Role for Bcl-6 in the generation and maintenance of memory CD8[+] T cells

2002 • 192 citations

Expression of IL-7 receptor α is necessary but not sufficient for the formation of memory CD8 T cells during viral infection

2007 • 185 citations

Cytokine-Dependent Blimp-1 Expression in Activated T Cells Inhibits IL-2 Production

2007 • 178 citations

Mice Deficient in OX40 and CD30 Signals Lack Memory Antibody Responses because of Deficient CD4 T Cell Memory

2005 • 158 citations

Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival

2008 • 150 citations

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1

2007 • 150 citations

Plasmacytic Transcription Factor Blimp-1 Is Repressed by Bach2 in B Cells

2006 • 150 citations

Bcl6 Acts as an Amplifier for the Generation and Proliferative Capacity of Central Memory CD8+ T Cells

2004 • 144 citations

Blimp-1 Attenuates Th1 Differentiation by Repression of ifng, tbx21, and bcl6 Gene Expression

2008 • 136 citations

Endoplasmic Reticulum Stress Regulator XBP-1 Contributes to Effector CD8+ T Cell Differentiation during Acute Infection

2008 • 135 citations

Strength of Stimulus and Clonal Competition Impact the Rate of Memory CD8 T Cell Differentiation

2007 • 132 citations

Temporal loss of the activated L-selectin-low phenotype for virus-specific CD8+ memory T cells.

1995 • 130 citations

IL-12 Signaling Drives CD8+ T Cell IFN-γ Production and Differentiation of KLRG1+ Effector Subpopulations during Toxoplasma gondii Infection

2008 • 120 citations

Serine Protease Inhibitor 6 Protects Cytotoxic T Cells from Self-Inflicted Injury by Ensuring the Integrity of Cytotoxic Granules

2006 • 116 citations

Manipulating the Rate of Memory CD8+ T Cell Generation after Acute Infection

2007 • 110 citations

Anti‐OX40 stimulation in vivo enhances CD8⁺ memory T cell survival and significantly increases recall responses

2006 • 95 citations

Activation-dependent induction of Blimp-1

2008 • 85 citations

Loss of T cell receptor-induced Bmi-1 in the KLRG1⁺senescent CD8⁺T lymphocyte

2007 • 84 citations

BCL6b mediates the enhanced magnitude of the secondary response of memory CD8 ⁺ T lymphocytes

2005 • 77 citations

DNA Methylation by DNA Methyltransferase 1 Is Critical for Effector CD8 T Cell Expansion

2006 • 48 citations

The Granule Pathway of Programmed Cell Death

2005 • 43 citations

Differential Survival of Cytotoxic T Cells and Memory Cell Precursors

2007 • 29 citations

A Transgenic Mouse Model Genetically Tags All Activated CD8 T Cells

2003 • 26 citations