Adenosine Acts through a Novel Extracellular Receptor to Inhibit Granule Exocytosis by Natural Killer Cells

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

1989 • 3,308 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX. The quantitation of natural killer cell activity

1981 • 703 citations

Cardiovascular purinoceptors

1990 • 666 citations

Cloned adenosine A3 receptors: Pharmacological properties, species differences and receptor functions

1994 • 395 citations

TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells).

1985 • 373 citations

Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A

1992 • 243 citations

Adenosine and Adenine Nucleotides As Regulators of Cellular Function

2024 • 197 citations

Purine and Pyrimidine Metabolism

1995 • 193 citations

Adenosine transporters

1996 • 188 citations

Thiobenzyl benzyloxycarbonyl-l-lysinate, substrate for a sensitive colorimetric assay for trypsin-like enzymes

1979 • 176 citations

Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.

1987 • 128 citations

Purinoceptor nomenclature: A status report

1993 • 91 citations

Adenosine inhibits the adhesion of anti-CD3-activated killer lymphocytes to adenocarcinoma cells through an A3 receptor.

1994 • 86 citations

Receptors for adenosine and adenine nucleotides

1991 • 69 citations

Factors, including transforming growth factor β, released in the glioblastoma residual cavity, impair activity of adherent lymphokine-activated killer cells

1993 • 64 citations

Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF–, and chemotactic peptide–induced degranulation in single adherent neutrophils

1992 • 63 citations

Differential effects of various pharmacological agents on the cytolytic reaction mechanism of the human natural killer lymphocyte: further resolution of programming for lysis and KCIL into discrete stages.

1982 • 60 citations

Adenosine receptors and modulation of natural killer cell activity by purine nucleosides.

1990 • 54 citations

Species differences in sensitivity of nucleoside transport in erythrocytes and cultured cells to inhibition by nitrobenzylthioinosine, dipyridamole, dilazep and lidoflazine

1988 • 48 citations

Regulation of Macrophage Lysosomal Secretion by Adenosine, Adenosine Phosphate Esters, and Related Structural Analogues of Adenosine

1985 • 42 citations

Adrenergic modulation of human polymorphonuclear leukocyte activation. Potentiating effect of adenosine

1991 • 42 citations

Differential expression of granzyme A and granzyme B proteases and their secretion by fresh rat natural killer cells (NK) and lymphokine‐activated killer cells with NK phenotype (LAK‐NK)

1992 • 41 citations

Adenosine potentiates immunological histamine release from rat mast cells by a novel cyclic AMP‐independent cell‐surface action

1985 • 40 citations

Inhibition of Human NK Cell Cytotoxicity by Induction of Cyclic AMP Depends on Impaired Target Cell Recognition

1983 • 40 citations

Adenosine antagonists

1989 • 38 citations

Direct evidence for release of pore-forming protein during NK cellular lysis

1992 • 31 citations

Expression of perforin in murine natural killer cells and cytotoxic T lymphocytes in vivo

1992 • 30 citations

Inhibition by adenosine of histamine and leukotriene release from human basophils

1989 • 21 citations

Expression and utilization of chymotrypsin-like but not trypsin-like serine protease enzymes by nonspecific T killer cells activated by anti-CD3 monoclonal antibody

1992 • 18 citations

Selective modulation of antibody response and natural killer cell activity by purine nucleoside analogues.

1988 • 18 citations

Adenosine regulates the Ca2+ sensitivity of mast cell mediator release.

1988 • 18 citations

Irreversible inhibition of human natural killer cell natural cytotoxicity by modification of the extracellular membrane by the adenine nucleotide analog 5′-p-(fluorosulfonyl)benzoyl adenosine

1995 • 17 citations

Adenosine inhibits immunoglobulin E-dependent histamine secretion from human basophil leukocytes by two independent mechanisms.

1987 • 16 citations

Role of natural killer cells in the modulation of primary antibody production by purine nucleosides and their analogs

1990 • 14 citations

Substrate-specific proteases (BLT-esterase) are localized predominantly in the natural killer cells of unprimed mice

1993 • 12 citations

Inhibition of Interleukin‐2 Messenger RNA in Mouse Lymphocytes by 2′‐Deoxycoformycin and Adenosine Metabolites

1985 • 5 citations