Inhibition of Interleukin‐2 Messenger RNA in Mouse Lymphocytes by 2′‐Deoxycoformycin and Adenosine Metabolites

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

Macrophage-independent activation of helper T cells. I. Production of Interleukin 2.

1980 • 219 citations

The biochemical and clinical consequences of 2'-deoxycoformycin in refractory lymphoproliferative malignancy

1981 • 199 citations

Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes.

1984 • 141 citations

S -Adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin

1979 • 124 citations

Inhibition of maturation of human precursor lymphocytes by coformycin, and inhibitor of the enzyme adenosine deaminase

1976 • 107 citations

Clinical pharmacology of deoxycoformycin

1981 • 107 citations

Kinetics of induction and molecular size of mRNAs encoding human interleukin-2 and γ-interferon

1982 • 104 citations

Human T-cell growth factor: partial amino acid sequence, cDNA cloning, and organization and expression in normal and leukemic cells.

1984 • 101 citations

Clinical pharmacology of deoxycoformycin

1981 • 91 citations

Phorbol myristic acetate enhances the production of Interleukin 2

1981 • 65 citations

In vitro metabolism of deoxycoformycin in human T lymphoblastoid cells. Phosphorylation of deoxycoformycin and incorporation into cellular DNA.

1984 • 41 citations

Biological activity of mRNA immobilized on nitrocellulose in NaI.

1983 • 41 citations

Animal model for immune dysfunction associated with adenosine deaminase deficiency.

1980 • 36 citations

Effect of 2'-deoxycoformycin on erythroid, granulocytic, and T- lymphocyte colony growth

1981 • 23 citations

Distribution of Lymphocyte Messenger RNA during Stimulation by Phytohaemagglutinin

1979 • 22 citations

In vitro effects of adenosine deaminase inhibitors on lymphocyte mitogen responsiveness in the mouse

1981 • 17 citations

The metabolism of 2'-deoxycoformycin by L1210 cells invitro

1979 • 16 citations

Specific immunosuppressive effects of constant infusion of 2'-deoxycoformycin.

1981 • 16 citations

Inability of immunocompetent thymocytes to produce T-cell growth factor under adenosine deaminase deficiency conditions

1981 • 16 citations

Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.

1980 • 14 citations

S-adenosylhomocysteine hydrolase activity, deoxyadenosine triphosphate accumulation, and competence of thymocyte and spleen leucocyte response to mitogens in coformycin-treated mice

1983 • 9 citations

Morphologic Changes and Immunohistochemical Localization of Adenosine Deaminase in Tissues of Rats Given Injections of 2'-Deoxycoformycin<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 3 citations

Vergleichende Untersuchungen über biologische Wirkungen von Hybridenwein

1961 • 2 citations