Differential regulation of Cdc2 and Aurora-A in Xenopus oocytes: a crucial role of phosphatase 2A

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1988 • 1,699 citations

Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

1990 • 1,627 citations

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

1971 • 1,553 citations

The cellular geography of Aurora kinases

2003 • 1,118 citations

Uncoupling of Obesity from Insulin Resistance Through a Targeted Mutation in aP2 , the Adipocyte Fatty Acid Binding Protein

1996 • 900 citations

Processing of Adenovirus 2-Induced Proteins

1973 • 762 citations

Aurora-A and an Interacting Activator, the LIM Protein Ajuba, Are Required for Mitotic Commitment in Human Cells

2003 • 610 citations

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1984 • 610 citations

Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts

1996 • 506 citations

Regulation of the cdc25 protein during the cell cycle in Xenopus extracts

1992 • 430 citations

Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA

2000 • 373 citations

A Novel Mechanism for Activation of the Protein Kinase Aurora A

2003 • 358 citations

A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions

1983 • 342 citations

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

2003 • 341 citations

Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity.

1992 • 294 citations

Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase.

1993 • 291 citations

Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid.

1990 • 244 citations

14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 inXenopusEgg Extracts

1998 • 214 citations

G ₂ arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A

2002 • 198 citations

The Polo-like kinase Plx1 is a component of the MPF amplification loop at the G2/M-phase transition of the cell cycle in Xenopus eggs

1998 • 190 citations

Interaction and Feedback Regulation between STK15/BTAK/Aurora-A Kinase and Protein Phosphatase 1 through Mitotic Cell Division Cycle

2001 • 189 citations

Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes

1989 • 179 citations

APC/Fizzy‐Related targets Aurora‐A kinase for proteolysis

2002 • 162 citations

PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation

2003 • 152 citations

New B-type cyclin synthesis is required between meiosis I and II duringXenopusoocyte maturation

2001 • 147 citations

Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine.

1992 • 130 citations

Tyrosine phosphorylation of p34cdc2 and p42 during meiotic maturation of Xenopus oocyte: Antagonistic action of okadaic acid and 6-DMAP

1991 • 128 citations

Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3

2004 • 122 citations

Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine

1992 • 115 citations

Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein

2004 • 109 citations

Inhibition of cdc2 activation by INH/PP2A.

1994 • 103 citations

Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity

1990 • 98 citations

Phosphatase 2A and Polo kinase, two antagonistic regulators of Cdc25 activation and MPF auto-amplification

1999 • 97 citations

Two Distinct Mechanisms Control the Accumulation of Cyclin B1 and Mos inXenopusOocytes in Response to Progesterone

1999 • 88 citations

Protein phosphatase-1 is involved in Xenopus oocyte maturation

1981 • 86 citations

Regulation of ATP, Mg-Dependent Protein Phosphatases

1988 • 77 citations

Thr-161 Phosphorylation of Monomeric Cdc2

2002 • 77 citations

Regulation of ATP—Mg-Dependent Protein Phosphatase

1984 • 76 citations

Progesterone regulates the accumulation and the activation of Eg2 kinase in Xenopus oocytes

2000 • 76 citations

MPF Amplification inXenopusOocyte Extracts Depends on a Two-Step Activation of Cdc25 Phosphatase

1998 • 68 citations

Mechanism of Inhibition of Protein Phosphatase 1 by DARPP-32: Studies with Recombinant DARPP-32 and Synthetic Peptides

1995 • 63 citations

Cdc2-Cyclin B Triggers H3 Kinase Activation of Aurora-A in Xenopus Oocytes

2003 • 60 citations

pEg2 Aurora-A Kinase, Histone H3 Phosphorylation, and Chromosome Assembly in Xenopus Egg Extract

2001 • 58 citations

Involvement of Aurora A Kinase during Meiosis I-II Transition inXenopus Oocytes

2003 • 48 citations

From progesterone to active Cdc2 in Xenopus oocytes: a puzzling signalling pathway

2001 • 39 citations

Modulation of the substrate specificity of the polycation‐stimulated protein phosphatase from Xenopus laevis oocytes

1988 • 38 citations

The PR55 and PR65 Subunits of Protein Phosphatase 2A from Xenopus laevis. Molecular Cloning and Developmental Regulation of Expression

1995 • 36 citations

A Study on Gonadotropin Action in the Induction of Oocyte Maturation in Xenopus laevis1

1974 • 31 citations

A Feedback Loop in the Polo-like Kinase Activation Pathway

2004 • 26 citations

The PR55 and PR65 Subunits of Protein Phosphatase 2A from Xenopus laevis

1995 • 11 citations

Okadaic acid, a protein phosphatase inhibitor, increases the calcium transients in isolated ferret ventricular muscle

1991 • 8 citations

Deleted Work

1955 • 0 citations