Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.

1977 • 844 citations

Protein Phosphatases: Properties and Role in Cellular Regulation

1983 • 645 citations

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1984 • 610 citations

Separation and Characterization of Two Phosphorylase Phosphatase Inhibitors from Rabbit Skeletal Muscle

1976 • 439 citations

[37] Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1988 • 418 citations

A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions

1983 • 342 citations

Peptides: Structure and biological function

1980 • 335 citations

Prediction of chain turns in globular proteins on a hydrophobic basis

1978 • 334 citations

Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture

1980 • 306 citations

The Regulation of Glycogen Metaabolism

1978 • 297 citations

cGMP-dependent protein kinase, a chimeric protein homologous with two separate protein families

1984 • 292 citations

The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver

1976 • 214 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus

1984 • 209 citations

Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP-dependent protein kinase.

1976 • 206 citations

Mammalian brain phosphoproteins as substrates for calcineurin.

1984 • 195 citations

Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity.

1986 • 187 citations

Role of protein phosphorylation in neuronal signal transduction ¹

1989 • 186 citations

The Protein Phosphatases Involved in Cellular Regulation. 5. Purification and Properties of a Ca2+ /Calmodulin-Dependent Protein Phosphatase (2B) from Rabbit Skeletal Muscle

1983 • 186 citations

Amino acid sequence of the catalytic subunit of bovine type II adenosine cyclic 3',5'-phosphate-dependent protein kinase

1983 • 185 citations

Activation of calcineurin by limited proteolysis.

1983 • 178 citations

Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II

1989 • 175 citations

Complete Primary Structure of Protein Phosphatase Inhibitor‐1 from Rabbit Skeletal Muscle

1982 • 163 citations

Comparison of the substrate specificity of adenosine 3':5'-monophosphate- and guanosine 3':5'-monophosphate-dependent protein kinases. Kinetic studies using synthetic peptides corresponding to phosphorylation sites in histone H2B.

1979 • 152 citations

DARPP-32, a dopamine- and adenosine 3‘:5‘-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.

1984 • 142 citations

Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method

1975 • 141 citations

The Hormonal Control of Glycogen Metabolism

1979 • 131 citations

Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases.

1980 • 121 citations

Synthetic peptides corresponding to the site phosphorylated in 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as substrates of cyclic nucleotide-dependent protein kinases.

1986 • 116 citations

[40] Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle

1988 • 109 citations

DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.

1986 • 105 citations

Dopaminergic regulation of protein phosphorylation in the striatum: DARPP-32

1987 • 100 citations

DARPP-32, a dopamine- and adenosine 3‘:5‘-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.

1984 • 93 citations

A specific substrate from rabbit cerebellum for guanosine-3‘:5‘-monophosphate-dependent protein kinase. III. Amino acid sequences at the two phosphorylation sites.

1981 • 88 citations

Phosphorylation of synthetic peptide analogs of rabbit cardiac troponin inhibitory subunit by the cyclic AMP-dependent protein kinase.

1979 • 77 citations

Dephosphorylation of phosphoproteins and synthetic phosphopeptides. Study of the specificity of the polycation-stimulated and MgATP-dependent phosphorylase phosphatases.

1987 • 74 citations

A Kinetic Analysis of the Effects of Inhibitor-1 and Inhibitor-2 on the Activity of Protein Phosphatase-1

1983 • 74 citations

Characterization of the phosphotyrosyl protein phosphatase activity of calmodulin-dependent protein phosphatase.

1986 • 65 citations

Isolation and characterisation of active fragments of protein phosphatase inhibitor‐1 from rabbit skeletal muscle

1982 • 62 citations

Partial structure and hormonal regulation of rabbit liver inhibitor-1; distribution of inhibitor-1 and inhibitor-2 in rabbit and rat tissues

1989 • 55 citations

The structural requirements of substrates of cyclic AMP‐dependent protein kinase

1982 • 50 citations

Hormonal regulation of protein dephosphorylation. Identification and hormonal regulation of protein phosphatase inhibitor-1 in rat adipose tissue.

1983 • 49 citations

DARPP‐32 and Phosphatase Inhibitor‐1, Two Structurally Related Inhibitors of Protein Phosphatase‐1, Are Both Present in Striatonigral Neurons

1988 • 49 citations

Synthetic peptides reproducing the site phosphorylated by cAMP‐dependent protein kinase in protein phosphatase inhibitor‐1

1983 • 42 citations

Synthetic fragments of protamines as model substrates for rat liver cyclic AMP-dependent protein kinase

1981 • 38 citations

Phosphopeptide substrates of a phosphoprotein phosphatase from rat liver.

1980 • 25 citations

Identification of pseudo ‘phosphothreonyl-specific’ protein phosphatase T with a fraction of polycation-stimulated protein phosphatase 2A

1988 • 22 citations

[38] Protein phosphatase-2B from rabbit skeletal muscle: A Ca2+-Dependent, Calmodulin-Stimulated Enzyme

1988 • 18 citations