Gβγ-independent constitutive association of Gαswith SHP-1 and angiotensin II receptor AT2is essential in AT2-mediated ITIM-independent activation of SHP-1
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References (42)
International union of pharmacology. XXIII. The angiotensin II receptors.
2000 • 2,055 citations
The Many Faces of G Protein Signaling
1998 • 1,137 citations
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
1995 • 956 citations
REGULATION OF IMMUNE RESPONSES THROUGH INHIBITORY RECEPTORS
1999 • 947 citations
Protein sequence similarity searches using patterns as seeds
1998 • 329 citations
Dephosphorylation of Sp1 by Protein Phosphatase 1 Is Involved in the Glucose-mediated Activation of the Acetyl-CoA Carboxylase Gene
1996 • 228 citations
Angiotensin II type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase
1997 • 225 citations
A Novel Phosphotyrosine Motif with a Critical Amino Acid at Position −2 for the SH2 Domain-mediated Activation of the Tyrosine Phosphatase SHP-1
1997 • 199 citations
Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor.
1996 • 188 citations
Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction
1994 • 182 citations
The angiotensin II type 2 receptor: an enigma with multiple variations
2000 • 180 citations
Renal proximal tubular AT2 receptor: signaling and transport.
1999 • 179 citations
Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils
2002 • 176 citations
The Emerging Field of Receptor-Mediated Inhibitory Signaling: SHP or SHIP?
1996 • 174 citations
Identification of a Domain in the Angiotensin II Type 1 Receptor Determining Gq Coupling by the Use of Receptor Chimeras
1995 • 169 citations
The Tyrosine Phosphatase SHP-1 Associates with the sst2 Somatostatin Receptor and Is an Essential Component of sst2-mediated Inhibitory Growth Signaling
1997 • 168 citations
Mutation of Asp74 of the rat angiotensin II receptor confers changes in antagonist affinities and abolishes G-protein coupling.
1993 • 162 citations
The Active State of the AT1 Angiotensin Receptor Is Generated by Angiotensin II Induction
1996 • 150 citations
Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases
2000 • 144 citations
Ligand-independent signals from angiotensin II type 2 receptor induce apoptosis
2000 • 137 citations
Regulation of angiotensin II-induced JAK2 tyrosine phosphorylation: roles of SHP-1 and SHP-2
1998 • 136 citations
Cytoplasmic protein tyrosine phosphatases SHP-1 and SHP-2: regulators of B cell signal transduction
2000 • 124 citations
The AT2 Receptor Selectively Associates with Giα2 and Giα3 in the Rat Fetus
1996 • 123 citations
Angiotensin and its AT2 receptor: new insights into an old system
2001 • 109 citations
Intracellular Third Loop Domain of Angiotensin II Type-2 Receptor
1996 • 109 citations
Modulation of GDP Release from Transducin by the Conserved Glu134-Arg135 Sequence in Rhodopsin
1996 • 105 citations
Role of Aromaticity of Agonist Switches of Angiotensin II in the Activation of the AT1 Receptor
1999 • 101 citations
Apical Proteins Stimulate Complement Synthesis by Cultured Human Proximal Tubular Epithelial Cells
1999 • 97 citations
The Phosphotyrosine Phosphatase PTP1D, but not PTP1C, Is an Essential Mediator of Fibroblast Proliferation Induced by Tyrosine Kinase and G Protein-coupled Receptors
1995 • 93 citations
Mechanism of Constitutive Activation of the AT1 Receptor: Influence of the Size of the Agonist Switch Binding Residue Asn111
1998 • 86 citations
Pivotal role of tyrosine phosphatase SHP-1 in AT2 receptor-mediated apoptosis in rat fetal vascular smooth muscle cell
2001 • 76 citations
Angiotensin II type 1 and type 2 receptors bind angiotensin II through different types of epitope recognition
1999 • 74 citations
Analysis of Functional Domains of Angiotensin II Type 2 Receptor Involved in Apoptosis
1999 • 71 citations
Octapeptide somatostatin analog SMS 201-995 induces translocation of intracellular PTP1C to membranes in MCF-7 human breast adenocarcinoma cells.
1996 • 70 citations
Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein.
1995 • 68 citations
A G sα mutant designed to inhibit receptor signaling through G s
1999 • 63 citations
Determination of the Binding Specificity of the SH2 Domains of Protein Tyrosine Phosphatase SHP-1 through the Screening of a Combinatorial Phosphotyrosyl Peptide Library
2000 • 59 citations
Specificity of the SH2 Domains of SHP-1 in the Interaction with the Immunoreceptor Tyrosine-Based Inhibitory Motif-Bearing Receptor gp49B
1999 • 59 citations
Angiotensin II Type 2 Receptor Inhibits Epidermal Growth Factor Receptor Transactivation by Increasing Association of SHP-1 Tyrosine Phosphatase
2001 • 45 citations
G-protein βγ Subunits Mediate Specific Phosphorylation of the Protein-tyrosine Phosphatase SH-PTP1 Induced by Lysophosphatidic Acid
1996 • 45 citations
Reversible inactivation of AT2 angiotensin II receptor from cysteine–disulfide bond exchange
2000 • 24 citations
Role of Transmembrane Helix IV in G-protein Specificity of the Angiotensin II Type 1 Receptor
1999 • 21 citations