CD40 is functionally expressed on human keratinocytes

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

1988 • 680 citations

A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

1989 • 527 citations

CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

1995 • 481 citations

Prevention of Collagen-Induced Arthritis with an Antibody to gp39, the Ligand for CD40

1993 • 471 citations

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.

1994 • 431 citations

Protection against Fas-dependent Thl-mediated apoptosis by antigen receptor engagement in B cells

1995 • 426 citations

Expression of functional CD40 by vascular endothelial cells.

1995 • 414 citations

Fas ligation induces apoptosis of CD40-activated human B lymphocytes.

1995 • 402 citations

Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.

1995 • 371 citations

Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes.

1995 • 368 citations

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion.

1996 • 349 citations

Tumor necrosis factor receptor superfamily members and their ligands

1994 • 313 citations

CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway.

1995 • 285 citations

Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors.

1990 • 261 citations

CD40 is functionally expressed on human thymic epithelial cells.

1992 • 261 citations

CD40 ligand and its role in X-linked hyper-IgM syndrome

1993 • 257 citations

Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells.

1995 • 248 citations

Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes

1994 • 246 citations

Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease.

1994 • 187 citations

Expression of Fas Antigen on Keratinocytes In Vivo and Induction of Apoptosis in Cultured Keratinocytes

1994 • 175 citations

Accessory cell function of keratinocytes for superantigens. Dependence on lymphocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction.

1993 • 171 citations

The role of bcl‐x_L in CD40‐mediated rescue from anti‐μ‐induced apoptosis in WEHI‐231 B lymphoma cells

1995 • 154 citations

In the absence of a CD40 signal, B cells are tolerogenic

1995 • 149 citations

Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo.

1995 • 146 citations

Cytokine networks in the skin.

1995 • 133 citations

Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells.

1995 • 129 citations

The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection

1994 • 128 citations

Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis.

1996 • 117 citations

Functional expression of CD40 antigen on human epidermal Langerhans cells.

1995 • 108 citations

Intralesional T-Lymphocyte Activation as a Mediator of Psoriatic Epidermal Hyperplasia

1995 • 107 citations

Recombinant CD40 ligand exerts potent biologic effects on T cells.

1994 • 77 citations

In situ expression of B7 and CD28 receptor families in human malignant melanoma: Relevance for T‐cell‐mediated anti‐tumor immunity

1995 • 57 citations

Cytokine Networks in the Skin.

1995 • 56 citations

Phorbol-12-Myristate-13-Acetate-Treated Human Keratinocytes Express B7-Like Molecules That Serve a Costimulatory Role in T-Cell Activation

1993 • 42 citations