Control of Cholesterol Turnover in the Mouse

Regulation of Absorption and ABC1-Mediated Efflux of Cholesterol by RXR Heterodimers

2000 • 1,285 citations

How Cells Handle Cholesterol

2000 • 1,230 citations

Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans

1993 • 880 citations

Cholesterol metabolism in the brain

2001 • 869 citations

Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene

1997 • 797 citations

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

2000 • 543 citations

Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat.

1996 • 537 citations

ABCA1: the gatekeeper for eliminating excess tissue cholesterol

2001 • 460 citations

Oxysterol biosynthetic enzymes

2000 • 362 citations

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice

2001 • 291 citations

Very-low-density lipoprotein assembly and secretion

2001 • 287 citations

ABCA1-mediated transport of cellular cholesterol and phospholipids to HDL apolipoproteins

2000 • 260 citations

Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface

2000 • 252 citations

Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

1998 • 251 citations

Specific Docking of Apolipoprotein A-I at the Cell Surface Requires a Functional ABCA1 Transporter

2001 • 209 citations

Structure, function and regulation of the ABC1 gene product

2001 • 202 citations

Disruption of the Sterol 27-Hydroxylase Gene in Mice Results in Hepatomegaly and Hypertriglyceridemia

2000 • 198 citations

Membrane Lipid Domains Distinct from Cholesterol/Sphingomyelin-Rich Rafts Are Involved in the ABCA1-mediated Lipid Secretory Pathway

2001 • 191 citations

Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse.

1995 • 189 citations

ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism

2001 • 134 citations

Sterol-modulated Glycolipid Sorting Occurs in Niemann-Pick C1 Late Endosomes

2001 • 111 citations

Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration

1998 • 110 citations

Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets

1998 • 109 citations

Cholesterol Is Sequestered in the Brains of Mice with Niemann-Pick Type C Disease but Turnover Is Increased

2000 • 105 citations

Cholesterol accumulation in tissues of the Niemann-Pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ

1999 • 93 citations

Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma.

1996 • 85 citations

REMOVED: The caveolin triad: caveolae biogenesis, cholesterol trafficking, and signal transduction

2001 • 85 citations

Role of liver in the synthesis of cholesterol and the clearance of low density lipoproteins in the cynomolgus monkey

1995 • 83 citations

Cellular and physiological roles of SR-BI, a lipoprotein receptor which mediates selective lipid uptake

2000 • 66 citations

Cholesterol and bile acid metabolism in moderately advanced, stable cirrhosis of the liver

1979 • 50 citations

Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1)

2000 • 50 citations

Regulation of fecal bile acid excretion in male golden Syrian hamsters fed a cereal-based diet with and without added cholesterol

1997 • 41 citations

Identification of a metabolic difference accounting for the hyper- and hyporesponder phenotypes of cynomolgus monkey

1997 • 40 citations

Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI

2000 • 40 citations