Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI

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Identification of a Nuclear Receptor for Bile Acids

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Molecular physiology of reverse cholesterol transport.

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Hepatic Scavenger Receptor BI Promotes Rapid Clearance of High Density Lipoprotein Free Cholesterol and Its Transport into Bile

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Disruption of Cholesterol 7α-Hydroxylase Gene in Mice

1996 • 265 citations

Markedly Reduced Bile Acid Synthesis but Maintained Levels of Cholesterol and Vitamin D Metabolites in Mice with Disrupted Sterol 27-Hydroxylase Gene

1998 • 263 citations

Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

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Regulation of rates of cholesterol synthesis in vivo in the liver and carcass of the rat measured using [3H]water.

1980 • 228 citations

Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I.

1992 • 206 citations

Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat

1991 • 194 citations

Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse.

1995 • 189 citations

Nuclear receptor regulation of cholesterol and bile acid metabolism

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Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster.

1994 • 145 citations

27-Hydroxycholesterol: production rates in normal human subjects

1999 • 144 citations

High density lipoproteins, but not other lipoproteins, provide a vehicle for sterol transport to bile.

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Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein

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Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration

1998 • 110 citations

Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets

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Two 7α‐hydroxylase enzymes in bile acid biosynthesis

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Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver

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Regulation of Bile Acid Biosynthesis

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Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice☆☆☆

1998 • 94 citations

ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes

1997 • 94 citations

Cholesterol accumulation in tissues of the Niemann-Pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ

1999 • 93 citations

Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma.

1996 • 85 citations

Hepatocellular transport and secretion of biliary lipids

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[46] Reversed-phase high-performance liquid chromatography assay of cholesterol 7α-hydroxylase

1991 • 56 citations

Kinetic parameters for high density lipoprotein apoprotein AI and cholesteryl ester transport in the hamster.

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Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1)

2000 • 50 citations

Kinetic characteristics and regulation of HDL cholesteryl ester and apolipoprotein transport in the apoA-I-/- mouse

1998 • 44 citations

Regulation of fecal bile acid excretion in male golden Syrian hamsters fed a cereal-based diet with and without added cholesterol

1997 • 41 citations

The uptake of cholesterol at the small‐intestinal brush border membrane is inhibited by apolipoproteins

1997 • 23 citations

Dietary cholesterol and the mechanisms of cholesterol absorption

1999 • 13 citations

Hyposecretion of biliary phospholipids (PL) significantly decreases the intestinal absorption of cholesterol (Ch) in Mdr2(−/−) and (+/−) mice

1998 • 11 citations