Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

The Effect of Adjuvant Chemotherapy on Relapse-Free Survival in Patients with Osteosarcoma of the Extremity

1986 • 1,164 citations

Actions of Insulin-Like Growth Factors

1985 • 1,141 citations

The Nature and Regulation of the Receptors for Insulin-Like Growth Factors

1985 • 639 citations

Insulin-like growth factors and cancer

1992 • 622 citations

Regulation of insulin-like growth factor I gene expression by growth hormone.

1986 • 558 citations

The insulin-like growth factor I receptor: a key to tumor growth?

1995 • 549 citations

Insulin-like growth factor receptor expression and function in human breast cancer.

1990 • 321 citations

Insulin-like Growth Factors and Cancer

1995 • 321 citations

Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas.

1986 • 293 citations

Two insulin-like growth factor I messenger RNAs are expressed in human liver.

1986 • 260 citations

Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors.

1990 • 242 citations

Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: a possible therapeutic target.

1996 • 225 citations

Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation.

1996 • 160 citations

The gene structure of the insulin-like growth factor family

1989 • 143 citations

Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid.

1995 • 126 citations

Roles of insulinlike growth factor 1 (IGF-1) and the IGF-1 receptor in epidermal growth factor-stimulated growth of 3T3 cells.

1992 • 110 citations

Insulin‐like growth factor I receptor is required for the mitogenic and transforming activities of the platelet‐derived growth factor receptor

1995 • 93 citations

Inhibition of Growth of Human Osteosarcomas by Antagonists of Growth Hormone-Releasing Hormone

1995 • 92 citations

Inhibition of Metastatic Behavior of Murine Osteosarcoma by Hypophysectomy

1992 • 83 citations

PRIMARY BONE-FORMING TUMOURS AND THEIR RELATIONSHIP TO SKELETAL GROWTH

1958 • 74 citations

Failure of the bovine papillomavirus to transform mouse embryo fibroblasts with a targeted disruption of the insulin-like growth factor I receptor genes

1995 • 73 citations

Modulation of insulin-like growth factor I (IGF-I) receptors and membrane-associated IGF-binding proteins in endometrial cancer cells by estradiol.

1995 • 68 citations

Insulin-like growth factor 1 (IGF-1) receptors, IGF-1, and IGF-2 are expressed in primary human sarcomas.

1995 • 60 citations

The role of the insulin-like growth factor I receptor in the transformation by simian virus 40 T antigen.

1994 • 58 citations

Mutant IGF-I Receptors as Dominant Negatives for Growth and Transformation

1995 • 57 citations

Osteogenic Sarcoma; An Analysis of the Age and Sex Incidence

1955 • 54 citations

Expression of Insulinlike Growth Factor (IGF) and IGF-Binding Protein Genes in Human Lung Tumor Cell Lines

1992 • 53 citations

The role of chemotherapy in osteogenic sarcoma

1995 • 26 citations

Growth Regulation of the Human Papillary Thyroid Cancer Cell Line by Protein Tyrosine Kinase and cAMP-Dependent Protein Kinase.

1994 • 15 citations

The Expression of mRNA for Insulin-Like Growth Factors and Their Receptor in Giant Cell Tumors of Human Bone

1996 • 11 citations

Metastatic Behavior of the RIF-1 Murine Fibrosarcoma: Inhibited by Hypophysectomy and Partially Restored by Growth Hormone Replacement

1994 • 11 citations

Insulin-Like Growth Factor II: Complexity of Biosynthesis and Receptor Binding

1991 • 10 citations

Human biology and epidemiology of childhood bone cancers: a review.

1985 • 10 citations

Insulin-like growth factor-I is an autocrine regulator for the brain metastatic variant of a human non-small cell lung cell line

1995 • 9 citations

Hormonal evaluation in patients with osteosarcoma

1985 • 8 citations