A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

2003 • 1,115 citations

Rab7: A Key to Lysosome Biogenesis

2000 • 1,038 citations

α-lnhibin is a tumour-suppressor gene with gonadal specificity in mice

1992 • 887 citations

Gradient Formation of the TGF-β Homolog Dpp

2000 • 606 citations

Extracellular Regulation of BMP Signaling in Vertebrates: A Cocktail of Modulators

2002 • 602 citations

Id Genes Are Direct Targets of Bone Morphogenetic Protein Induction in Embryonic Stem Cells

1999 • 514 citations

Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis

2000 • 496 citations

Evidence from normal expression and targeted misexpression that Bone Morphogenetic Protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis

1996 • 480 citations

Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis

2004 • 355 citations

Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene

2001 • 338 citations

Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development

1999 • 330 citations

CHIP activates HSF1 and confers protection against apoptosis and cellular stress

2003 • 313 citations

Stimulation of Id1 Expression by Bone Morphogenetic Protein Is Sufficient and Necessary for Bone Morphogenetic Protein–Induced Activation of Endothelial Cells

2002 • 303 citations

Different Routes of Bone Morphogenic Protein (BMP) Receptor Endocytosis Influence BMP Signaling

2006 • 240 citations

Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis

2004 • 217 citations

BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation

2003 • 214 citations

The BMP-Binding Protein Crossveinless 2 Is a Short-Range, Concentration-Dependent, Biphasic Modulator of BMP Signaling in Drosophila

2008 • 163 citations

Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila

2000 • 163 citations

Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling

2001 • 153 citations

Caveolin-1–Deficient Mice Have Increased Tumor Microvascular Permeability, Angiogenesis, and Growth

2007 • 147 citations

Vesicular Trafficking of Tyrosine Kinase Receptors and Associated Proteins in the Regulation of Signaling and Vascular Function

2006 • 130 citations

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis

2006 • 116 citations

Creation of a Sog Morphogen Gradient in the Drosophila Embryo

2002 • 108 citations

von Willebrand Factor Type C Domain-containing Proteins Regulate Bone Morphogenetic Protein Signaling through Different Recognition Mechanisms

2007 • 107 citations

Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation

2006 • 107 citations

A Novel Procedure for Pre-embedding Double Immunogold–Silver Labeling at the Ultrastructural Level

2001 • 105 citations

Cleavages within the Prodomain Direct Intracellular Trafficking and Degradation of Mature Bone Morphogenetic Protein-4

2004 • 101 citations

Crossveinless-2 Is a BMP Feedback Inhibitor that Binds Chordin/BMP to Regulate Xenopus Embryonic Patterning

2008 • 100 citations

Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone

2005 • 81 citations

Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins

2004 • 73 citations

The Bone Morphogenetic Protein Antagonist Noggin Regulates Mammalian Cardiac Morphogenesis

2007 • 61 citations

A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration

2004 • 60 citations

Gene expression profiles identify a role for cyclooxygenase 2–dependent prostanoid generation in BMP6-induced angiogenic responses

2006 • 58 citations

Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade

2004 • 39 citations

The Low pH in Trans-Golgi Triggers Autocatalytic Cleavage of Pre-α-inhibitor Heavy Chain Precursor

2000 • 30 citations