Recognition of nascent polypeptides for targeting and folding

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Signal sequences

1985 • 2,179 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR

1988 • 823 citations

Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfolded state depends on two chaperonin proteins and Mg-ATP

1989 • 737 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

Structural Characterization of a Partly Folded Apomyoglobin Intermediate

1990 • 708 citations

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1988 • 583 citations

Protein Translocation Across Membranes

1988 • 482 citations

Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle

1989 • 474 citations

Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig .alpha.-lactalbumin

1989 • 473 citations

Signal sequences

1989 • 417 citations

Theory and applications of the transferred nuclear overhauser effect to the study of the conformations of small ligands bound to proteins

1982 • 392 citations

Transient association of newly synthesized unfolded proteins with the heat-shock GroEL protein

1988 • 388 citations

The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

1990 • 372 citations

Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro.

1989 • 317 citations

The molecular chaperone concept.

1990 • 311 citations

The ‘molten globule’ state is involved in the translocation of proteins across membranes?

1988 • 275 citations

Stress proteins in biology and medicine

1990 • 273 citations

Phosphatidylglycerol is involved in protein translocation across Escherichia coli inner membranes

1988 • 263 citations

The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the beta-lactamase precursor.

1990 • 250 citations

How do polypeptides cross the mitochondrial membranes?

1990 • 246 citations

SecA interacts with secretory proteins by recognizing the positive charge at the amino terminus of the signal peptide in Escherichia coli.

1990 • 229 citations

Unity in Function in the Absence of Consensus in Sequence: Role of Leader Peptides in Export

1989 • 222 citations

Detection and characterization of a folding intermediate in barnase by NMR

1990 • 212 citations

Thesec andprl genes ofEscherichia coli

1990 • 174 citations

The precursor of beta-lactamase: purification, properties and folding kinetics.

1989 • 110 citations

Functional and Nonfunctional LamB Signal Sequences Can Be Distinguished by Their Biophysical Properties

1989 • 97 citations

SecA protein: Autoregulated initiator of secretory precursor protein translocation across theE. coli plasma membrane

1990 • 87 citations

Protein transport across the ER membrane

1990 • 75 citations

Functional dissection of the signal recognition particle

1988 • 70 citations

The Escherichia coli groE chaperonins.

1990 • 65 citations

SecB protein: A cytosolic export factor that associates with nascent exported proteins

1990 • 41 citations

A mitochondrial chaperonin: genetic, biochemical, and molecular characteristics.

1990 • 23 citations

The plastid chaperonin.

1990 • 20 citations